SKF 77434|CAS 300561-58-4|DC Chemicals

Cas No.:	300561-58-4
Synonyms:	SKF 77434,SKF-77434,SKF77434
SMILES:	Br.OC1=CC2=C(C=C1O)C(CN(CC=C)CC2)C1=CC=CC=C1
Formula:	C₁₉H₂₁NO₂^.HBr
M.Wt:	376.29

Description:

Selective dopamine D1-like receptor partial agonist (IC50 values are 19.7 and 2425 nM for binding to D1-like and D2-like receptors respectively). Centrally active following systemic administration in vivo.

Cat. No.	Product name	Field of application
DC26135	SKF 77434	Selective dopamine D1-like receptor partial agonist (IC50 values are 19.7 and 2425 nM for binding to D1-like and D2-like receptors respectively). Centrally active following systemic administration in vivo.
DC12379	SKF 38393	SKF 38393 is a partial agonist of the dopamine D1-like receptors D1 and D5 (Kis = 1 and ~0.5 nM, respectively).
DC10189	SCH 23390 hydrochloride	SCH 23390 hydrochloride is a potent dopamine receptor D1 antagonist with Ki values of 0.2 and 0.3 nM for the D1 and D5.
DC6911	pardoprunox (SLV308)	Pardoprunox(SLV-308) is a novel partial dopamine D2 and D3 receptor agonist and serotonin 5-HT1A receptor agonist; D2 (pKi = 8.1) and D3 receptor (pKi = 8.6) partial agonist (IA = 50% and 67%, respectively) and 5-HT1A receptor (pKi = 8.5) full agonist (IA
DC9675	Pardoprunox.HCl(SLV-308)	Pardoprunox hydrochloride is a novel partial dopamine D2 and D3 receptor agonist and serotonin 5-HT1A receptor agonist, D2 (pKi = 8.1) and D3 receptor (pKi = 8.6) partial agonist and 5-HT1A receptor (pKi = 8.5) full agonist.
DC8286	Brexpiprazole(OPC34712)	Brexpiprazole is a novel D2 dopamine partial agonist.