Sal003|cas 1164470-53-4

Cas No.:	1164470-53-4
Chemical Name:	Sal-003,SAL 003,SAL003
Synonyms:	Sal-003,SAL 003,SAL003
SMILES:	O=C(C=CC1C=CC=CC=1)NC(C(Cl)(Cl)Cl)NC(=S)NC1C=CC(Cl)=CC=1
Formula:	C₁₈H₁₅Cl₄N₃Os
M.Wt:	463.21
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:

Sal003 is a potent cell-permeable analog of the eIF2α phosphatase inhibitor Salubrinal with enhanced aqueous solubility.IC50 value:Target: eIF2α phosphatase inhibitorSal003 has been shown to prevent dephosphorylation of eIF-2α which has been shown to regulate the late phase of long-term potentiation (LTP) and memory (LTM). This enhanced phosphorylated state of eIF-2α is shown to prevent L-LTP and suppress memory in mice.

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