XP-59|SARS-CoV Mpro inhibitor|CAS 890402-73-0

Cas No.:	890402-73-0
Chemical Name:	XP-59
Synonyms:	XP-59 ;XP 59 ;XP59
SMILES:	CN(C)C1=CC=C(C=C1)C(=O)ON2C3=CC=CC=C3N=N2
Formula:	C₁₅H₁₄N₄O₂
M.Wt:	282.29
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:	XP-59 is a potent inhibitor of the SARS-CoV Mpro, with a Ki of 0.1 μM[1].
Target:	Ki: 0.1 nM (SARS-CoV Mpro)[1].
In Vitro:	The SARS-CoV main proteinase (Mpro) plays a central role in the formation of the viral replicase/transcriptase complex and is thus an ideal target for the development of suitable drugs[1].
References:	[1]. Verschueren KH, et al,. A structural view of the inactivation of the SARS coronavirus main proteinase by benzotriazole esters. Chem Biol. 2008 Jun;15(6):597-606.

Cat. No.	Product name	Field of application
DC39053	XP-59	XP-59 is a potent inhibitor of the SARS-CoV Mpro, with a Ki of 0.1 μM[1].The SARS-CoV main proteinase (Mpro) plays a central role in the formation of the viral replicase/transcriptase complex and is thus an ideal target for the development of suitable dru
DC39042	FGI-106	FGI-106 tetrahydrochloride is a potent and broad-spectrum inhibitor with inhibitory activity against multiple viruses. FGI-106 tetrahydrochloride is active against Ebola, Rift Valley and Dengue Fever viruses with EC50s of 100 nM, 800 nM and 400-900 nM, respectively. FGI-106 tetrahydrochloride also inhibits non-hemorrhagic fever viruses HCV and HIV-1 with EC50s of 200 nM and 150 nM, respectively[1].FGI-106 is a potent compound for COVID-19 treament.