(+)-corynoline|cas 18797-79-0|Supplied by DC Chem

Cas No.:	18797-79-0
SMILES:	[H][C@]12N(C)CC3=C([C@@]1(C)[C@@H](O)CC4=C2C=C(OCO5)C5=C4)C=CC6=C3OCO6
Formula:	C₂₁H₂₁NO₅
M.Wt:	367.399
Purity:	>98%,Standard References Grade
Sotrage:	4 Degree for 1 year, -20 degree for more than 2 years

Description:	Corynoline, isolated from Corydalis incise (Papaveraceae), is a reversible and noncompetitive acetylcholinesterase (AChE) inhibitor with an IC50 of 30.6 μM[1]. Corynoline exhibits anti-inflammatory activity by activating Nrf2[2].
References:	[1]. Kim DK. Inhibitory effect of corynoline isolated from the aerial parts of Corydalis incisa on the acetylcholinesterase. Arch Pharm Res. 2002 Dec;25(6):817-9. [2]. Liu B, et al. Corynoline Exhibits Anti-inflammatory Effects in Lipopolysaccharide (LPS)-Stimulated Human Umbilical Vein Endothelial Cells through Activating Nrf2. Inflammation. 2018 Oct;41(5):1640-1647.

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