AMG2850|CAS 1470018-52-0|DC Chemicals

Cas No.:	1470018-52-0
Chemical Name:	AMG2850
SMILES:	O=C(N1CCC2=C(N=CC=C2)[C@H]1C3=CC=C(C(F)(F)F)C=C3)N[C@@H](C)C(F)(F)F
Formula:	C₁₉H₁₇F₆N₃O
M.Wt:	417.35
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Cat. No.	Product name	Field of application
DC47323	TRPA1 Antagonist 3	TRPA1 Antagonist 3 is a photoswitchable TRPA1 agonist that enables optical control of the TRPA1 channel.
DC47322	4-(Phenyldiazenyl)benzoic acid	4-(Phenyldiazenyl)benzoic acid is a photosensitive and photoswitchable TRPA1 agonist that can be used as pharmacological tools for study of pain signaling.
DC47246	SB 452533	SB 452533 is a potent and selective TRPV1 antagonist with the pKb of 7.8.
DC46699	9-Phenanthrol	9-Phenanthrol (9-Hydroxyphenanthrene, Phenanthren-9-o, 9-Phenanthrenol) is a selective TRPM4 inhibitor with an IC50 in the range of 0.02 μM, without effects on TRPM5.
DC46466	Dihydrocapsiate	Dihydrocapsiate, as a compound of capsinoid family, is an orally active TRPV1 agonist. Dihydrocapsiate can be used for the research of metabolism disease.
DC46465	Capsiate	Capsiate, as a capsaicin analogue extracted from a non-pungent cultivar of CH-19 sweet red pepper, is an orally active agonist of TRPV1.
DC45871	Methyl kakuol	Methyl kakuol shows agonistic activity against TRPA1 with an EC50 of 0.27 µM.
DC45849	GSK2332255B	GSK2332255B is a potent, selective TRPC3 and TRPC6 antagonist with IC50s of 5 nM and 4 nM for rat TRPC3 and rat TRPC6. GSK2332255B shows ≥100-fold selectivity for TRPC3/6 over other calcium-permeable channels.
DC45289	OptoBI-1	OptoBI-1 is a photochromic TRPC3 agonist, which asts as a photopharmacological tool to control of neuronal firing.
DC45288	AMG2850	AMG2850 is a potent, orally bioavailable and selective transient receptor potential melastatin 8 (TRPM8) antagonist.