AXC-715 hydrochloride|CAS 2490497-93-1|DC Chemicals

Cas No.:	2490497-93-1
Chemical Name:	AXC-715 hydrochloride
SMILES:	NCCCCN1C(CCCC)=NC2=C1C3=CC=CC=C3N=C2N.[H]Cl
Formula:	C₁₈H₂₆ClN₅
M.Wt:	347.89
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Cat. No.	Product name	Field of application
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DC47091	Guretolimod	Guretolimod is a Toll-like receptor 7 (TLR7) agonist.
DC46566	RS 09 TFA	RS 09 TFA is a TLR4 agonist. RS 09 TFA promotes NF-κB nuclear translocation and induces inflammatory cytokine secretion in RAW264.7 macrophages in vitro. RS 09 TFA acts as an adjuvant in vivo; RS 09 TFA enhances X-15 specific antibody serum concentrations, when administered with X-15-KLH in mice.
DC46401	Kdo2-Lipid A ammonium	Kdo2-Lipid A ammonium is a chemically defined lipopolysaccharide (LPS) with endotoxin activity equal to LPS. Kdo2-Lipid A ammonium is highly selective for TLR4. Kdo2-Lipid A ammonium stimulates the release of both TNF and PGE2.
DC46271	Pepinh-TRIF TFA	Pepinh-TRIF (TFA) is a 30 aa peptide that blocks TIR-domain-containing adapter-inducing interferon-β (TRIF) signaling by interfering with TLR-TRIF interaction.
DC45889	Stepharine	Stepharine, an natural alkaloid, directly interactes with TLR4 and binds to the TLR4/MD2 complex (TLR4 inhibitor). Stepharine possesses anti-aging, anti-viral and anti-hypertensive effects.
DC45798	CAY10614	CAY10614 is a potent TLR4 antagonist. CAY10614 inhibits the lipid A-induced activation of TLR4, with an IC50 of 1.675 μM. CAY10614 can improve survival of mice in lethal endotoxin shock model.
DC45282	AXC-715 hydrochloride	AXC-715 hydrochloride is a TLR7/TLR8 dual agonist, extracted from patent WO2020168017 A1.
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