BMS-986339|CAS 2477873-64-4|DC Chemicals

Cas No.:	2477873-64-4
Chemical Name:	BMS-986339
SMILES:	CC(F)(C1=NC(C23CCC(CC2)(CC3)CN(C4=CC(C5=CC=C(C=C5)C(C)(O)C)=CC=C4)C([C@H]6C[C@@](O)(C6)C(F)(F)F)=O)=NO1)C
Formula:	C₃₅H₄₁F₄N₃O₄
M.Wt:	643.71
Purity:	98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Cat. No.	Product name	Field of application
DC71956	BMS-986339	BMS-986339 is an orally active, potent FXR agonist. BMS-986339 forms H-bond with His298 and ASN287 residues.
DC7040	WAY-362450 (XL335; Turofexorate isopropyl)	WAY-362450 (XL335; Turofexorate isopropyl) is a highly potent, selective, and orally active farnesoid X receptor (FXR) agonist with an EC50 of 4 nM.WAY-362450 is useful for dyslipidemia.
DC10737	Tropifexor (LJN452)	Tropifexor (LJN452) is a highly potent non-bile Acid FXR Agonist for the Treatment of Cholestatic Liver Diseases and Nonalcoholic Steatohepatitis (NASH).
DC10470	SB756050	SB-756050 is a Farnesoid X receptor (FXR) (NR1H4) agonist.
DC7430	Obeticholic acid (INT-747)	INT-747(Obeticholic acid; 6-ECDCA) is a potent and selective FXR agonist(EC50=99 nM) endowed with anticholestatic activity.
DC7566	GW-4064	GW 4064 is a selective, non-steroidal farnesoid X receptor (FXR) agonist (EC50 = 15 nM).
DC8071	Fexarine	Fexarine is a potent, selective farnesoid X receptor agonist.
DC8070	Fexarene	Fexarene is a potent, selective farnesoid X receptor agonist.
DC8085	Fexaramine	Fexaramine is a potent, selective FXR activator.
DC10868	Cilofexor	Cilofexor (GS-9674, GS9674) is novel specific, non-steroidal farnesoid X receptor (FXR) agonist that reduces liver fibrosis and ameliorates portal hypertension in rat NASH models.