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BRF110

Cat. No.: DC73845

Chemical Structure

2095489-35-1

For research use only. We do not sell to patients.

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Field of application

BRF110 is a potent, selective, brain penetrant and vivo active agonist of Nurr1-RXRα heterodimers with EC50 of 900 nM.

Chemicals Properties Biological activity Related products COA MSDS Datasheet

Cas No.:	2095489-35-1
Chemical Name:	BRF110
SMILES:	O=C(O)C1=CC=C(N(C2=NC(C3=CC=CC=C3)=NC(C(F)(F)F)=C2CC=C)C)C=C1
Formula:	C₂₂H₁₈F₃N₃O₂
M.Wt:	413.4

Cat. No.	Product name	Field of application
DC73847	XCT0135908	XCT0135908 (BRF001) is a highly selective activator of Nurr1-RXR heterodimers, stimulates dopamine (DA) neuron survival.
DC73846	SA00025	SA00025 is a potent, specific and brain penetrant agonist of Nurr1 (NR4A2) with EC50 of 2.5 nM in HEK293 cells transfected with full length human Nurr1.
DC73845	BRF110	BRF110 is a potent, selective, brain penetrant and vivo active agonist of Nurr1-RXRα heterodimers with EC50 of 900 nM.
DC73844	4A7C-301	4A7C-301 is a potent, selective, brain-penetrant agonist of nuclear receptor Nurr1 with EC50 of 6.53 uM, binds to Nurr1 ligand binding domain (LBD) with IC50 of 50 nM.

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