| Cas No.: | |
| Chemical Name: | C2NP sodium |
| Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Cat. No. | Product name | Field of application |
| DC40738 | (Rac)-Benpyrine | (Rac)-Benpyrine, a racemate of Benpyrine, is a potent and orally active TNF-α inhibitor. (Rac)-Benpyrine has the potential for TNF-α mediated inflammatory and autoimmune disease research. |
| DC79715 | idoBR1 | idoBR1 is an orally active amino acid with an amino sugar. idoBR1 can significantly inhibit LPS induced TNF-α production and MAPK signaling pathway. idoBR1 can inhibit bacteria and human sialidase. idoBR1 can inhibit bacterial and human sialidase and reduce the binding of CD44 to hyaluronic acid (HA). idoBR1 can reduce the release of pro-inflammatory factors and promote the generation of anti-inflammatory factors. idoBR1 can be used for research on inflammatory conditions. |
| DC78798 | MDL 201112 | MDL 201112 is a carbocyclic nucleoside. MDL 201112 can decrease TNF-α production and inhibit MHC class II Ia+ antigen expression. MDL 201112 can be used for the research of inflammation and immunology. |
| DC78677 | SKF 104351 | SKF 104351 is an orally active cytokine suppressive anti-inflammatory drug. SKF 104351 can inhibit TNF-α production. |
| DC78244 | t9,t11,c15-CLNA | t9,t11,c15-CLNA is a conjugated linolenic acid (CLNA) isomer produced by Lactobacillus plantarum ZS2058. t9,t11,c15-CLNA has the main activities of anti-inflammatory, antioxidant and improving intestinal barrier function. The regulatory mechanism of t9,t11,c15-CLNA includes upregulation of tight junction proteins, inhibition of pro-inflammatory cytokines (such as TNF-α, IL-6) and activation of antioxidant enzymes (such as SOD, CAT). t9,t11,c15-CLNA can be used in the study of inflammatory bowel diseases (such as colitis). |
| DC78001 | VR11 aptamer | VR11 aptamer is a DNA-based TNF-α inhibitor with a KD of 7.0 nM. VR11 aptamer prevents TNFα-induced apoptosis and NO production. VR11 aptamer has non-immunogenicity and does not raise immune responses when injected intraperitoneally into C57BL/6 mice model. VR11 aptamer can be used for inflammatory diseases research. |
| DC77868 | C2NP sodium | C2NP sodium is a single-strand DNA aptamer that targets CD30. The multivalent C2NP is able to induce oligomerization of CD30 receptors and, in effect, activate downstream signaling, which led to apoptosis of anaplastic large cell lymphoma (ALCL) cells. |
| DC77856 | aptTNF-α sodium | aptTNF-α sodium is a TNF-α-targeting aptamer that has tissue protective effect and systemic anti-inflammatory effect upon acute tissue injury using the mouse acute lung injury (ALI) and acute liver failure (ALF) models. |
| DC76161 | Resolvin D2 n-3 DPA | Resolvin D2 n-3 DPA is a specialized proresolving mediator (SPM). Resolvin D2 n-3 DPA (1 nM) can reduce the chemotaxis and adhesion of human neutrophils induced by TNF-α. Resolvin D2 n-3 DPA (100 ng/mouse; intravenous injection) can reduce neutrophil infiltration in the peritoneum and the levels of IL-6 and the chemokine (C-C motif) ligand 2 (CCL2) in a mouse model of inflammation induced by zinc oxide. |
| DC76160 | NSC 15830 hydrochloride | NSC 15830 (S-(1,2-Dichlorovinyl)-L-cysteine) hydrochloride is a nephrotoxin and metabolite of trichloroethylene. NSC 15830 hydrochloride inhibits pathogen-stimulated TNF-α. |

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