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CGH2466 dihydrochloride

  Cat. No.:  DC76398  
Chemical Structure
1177618-54-0
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Field of application
CGH 2466 dihydrochloride is an orally active adenosine A1, A2B and A3 receptor antagonist with the IC50 values of 19 nM, 21 nM, and 80 nM respectively. CGH 2466 dihydrochloride inhibits p38 MAPK (IC50 = 187~ 400 nM) and phosphodiesterase type 4D (IC50 = 22 nM). CGH 2466 dihydrochloride displays potent anti-inflammatory effects both in vitro and in vivo, and can be used for research on asthma and chronic obstructive pulmonary disease (COPD).
Chemicals PropertiesBiological activity Related products COA MSDS Datasheet
Cas No.: 1177618-54-0
Chemical Name: CGH2466 dihydrochloride
SMILES: NC1=NC(C2=CC=C(Cl)C(Cl)=C2)=C(C3=CC=NC=C3)S1.Cl.Cl
Formula: C14H11Cl4N3S
M.Wt: 395.13
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
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