ANR94|CAS 634924-89-3|DC Chemicals

Cas No.:	634924-89-3
Chemical Name:	ANR 94
Synonyms:	8-ethoxy-9-ethyl-9H-Purin-6-amine;9H-Purin-6-amine,8-ethoxy-9-ethyl-(9CI);ANR 94
SMILES:	NC1=C2N=C(OCC)N(CC)C2=NC=N1
Formula:	C₉H₁₃N₅O
M.Wt:	207.23242
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Publication:	[1]. Volpini R, et al. Adenosine A2A receptor antagonists: new 8-substituted 9-ethyladenines as tools for in vivo rat models of Parkinson's disease. ChemMedChem. 2009;4(6):1010-1019. [2]. Micioni Di Bonaventura MV, et al. Regulation of adenosine A2A receptor gene expression in a model of binge eating in the amygdaloid complex of female rats. J Psychopharmacol. 2019;33(12):1550-1561.

Description:	ANR-94 is a potent and selective adenosine A2A receptor (AA2AR) antagonist with an Ki of 46 nM for hAA2AR. ANR 94 has the potential for the research of Parkinson's disease.
References:	[1]. Volpini R, et al. Adenosine A2A receptor antagonists: new 8-substituted 9-ethyladenines as tools for in vivo rat models of Parkinson's disease. ChemMedChem. 2009;4(6):1010-1019. [2]. Micioni Di Bonaventura MV, et al. Regulation of adenosine A2A receptor gene expression in a model of binge eating in the amygdaloid complex of female rats. J Psychopharmacol. 2019;33(12):1550-1561.

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