CP-447697|CAS 1092847-21-6|DC Chemicals

Cas No.:	1092847-21-6
Chemical Name:	CP-447697
Synonyms:	1-Piperidinecarboxamide, 4-[(benzo[b]thien-3-ylcarbonyl)[2-(4-chlorophenyl)ethyl]amino]-N-(2,4-difluorophenyl)-;CP-447697
SMILES:	N1(C(NC2=CC=C(F)C=C2F)=O)CCC(N(C(C2=CSC3=CC=CC=C32)=O)CCC2=CC=C(Cl)C=C2)CC1
Formula:	C₂₉H₂₆ClF₂N₃O₂S
M.Wt:	554.05
Purity:	98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Cat. No.	Product name	Field of application
DC72349	CP-447697	CP-447697 is a lipophilic C5a receptor antagonist with an IC50 value of 31 nM. CP-447697 can be used for the research of inflammation.
DC44151	Complement factor D-IN-2	Complement factor D-IN-2 is an inhibitor of complement factor D extracted from patent WO2015130838A1, compound 190. Complement factor D-IN-2 targets factor D and inhibits the complement cascade at an early and essential point in the alternative complement pathway. Complement factor D-IN-2 can be used for the research of autoimmune diseases.
DC28985	(Z)-Leukadherin-1	(Z)-Leukadherin-1 (ADH-503 free base) is an orally active and allosteric CD11b agonist. (Z)-Leukadherin-1 leads to the repolarization of tumor-associated macrophages, reduction in the number of tumor-infiltrating immunosuppressive myeloid cells, and enhances dendritic cell responses.
DC11082	Danicopan (ACH-4471)	Danicopan (ACH-4471, ACH-0144471) is a highly potent, orally active Factor D inhibitor with Kd of 0.54 nM, inhibits the proteolytic activity of purified Factor D against substrate Factor B in complex with C3b, blocking production of Bb fragment IC50 of 15 nM.
DC11688	Avacopan	Avacopan is a potent, selective, orally availale C5aR (CD88) inhibitor with IC50 of 0.1 nM.