DYRK1-IN-1|CAS |DC Chemicals

Cas No.:
Chemical Name:	DYRK1-IN-1
SMILES:	CN(C1=NC(C2=C3C=CC=NN3N=C2)=CC=N1)C
Formula:	C₁₂H₁₂N₆
M.Wt:	240.26
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Cat. No.	Product name	Field of application
DC47679	Dyrk1A-IN-1	Dyrk1A-IN-1 is a triple inhibitor of Dyrk1A kinase activity (IC50 = 119 nM) and the aggregation of tau and α-syn oligomers.
DC46436	DYRK1-IN-1	DYRK1-IN-1 is a highly selective and ligand-efficient DYRK1A inhibitor. DYRK1-IN-1 inhibits DYRK1A phosphorylation activity with an IC50 value of 220 nM. DYRK1-IN-1 can be used for the research of central nervous system penetrant DYRK1A chemical probe.
DC45691	DYRKs-IN-1 hydrochloride	DYRKs-IN-1 hydrochloride is a potent DYRKs (Dual-specificity tyrosine-phosphorylation-regulated kinases) inhibitor with IC50s of 5 nM and 8 nM for DYRK1A and DYRK1B, respectively. DYRKs-IN-1 hydrochloride has antitumor activity.
DC10300	Tbid	tBID is a selective inhibitor of homeodomain–interacting protein kinase 2 (HIPK2) with an IC50 of 0.33 µM.