Elenestinib|CAS 2505078-08-8|DC Chemicals

Cas No.:	2505078-08-8
Chemical Name:	Elenestinib
SMILES:	OCCN1N=CC(C2=CN3N=CN=C(N4CCN(C5=NC=C([C@](C6=CC=C(F)C=C6)(N)C)C=N5)CC4)C3=C2)=C1
Formula:	C₂₇H₂₉FN₁₀O
M.Wt:	528.58
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Cat. No.	Product name	Field of application
DC72747	Elenestinib	Elenestinib (BLU-263) is a potent and orally active tyrosine kinase inhibitor. Elenestinib has the potential for the research of systemic mastocytosis (SM).
DC48359	Bezuclastinib	Bezuclastinib (PLX 9486; CGT9486) is a potent inhibitor of c-kit and c-kit D816V (0.0001
DC44837	M4205	M4205 is a c-KIT inhibitor, with an IC50 of 10 nM for c-KIT V654A. M4205 has high activity on c-KIT mutations in exon 11, 13, 17.
DC7219	OSI 930	OSI-930 is a potent inhibitor of Kit, KDR and CSF-1R with IC50 of 80 nM, 9 nM and 15 nM, respectively; also potent to Flt-1, c-Raf and Lck and low activity against PDGFRα/β, Flt-3 and Abl.
DC10082	ISCK03	ISCK03 is a cell-permeable inhibitor of SCF-mediated c-kit activation, completely blocking phosphorylation of c-kit in human melanoma cells at a concentration between 1 and 5 µM.
DC9585	c-Kit-IN-1(DCC-2618)	DCC-2618 is a small molecule inhibitor of c-Kit and PDGFR with IC50s of 6 nM/30 nM/13 nM for c-Kit/PDGFRα/PDGFRβ respectively.
DC10530	BLU-285 (Avapritinib)	BLU-285 is a potent and selective exon 17 mutant KIT kinase inhibitor with IC50 of 0.27 nM for KIT D816V.
DC7324	Amuvatinib (MP-470)	Amuvatinib (MP-470) is a potent and multi-targeted inhibitor of c-Kit, PDGFRα and Flt3 with IC50 of 10 nM, 40 nM and 81 nM, respectively.