Exicorilant|CAS 1781244-77-6|DC Chemicals

Cas No.:	1781244-77-6
Chemical Name:	Exicorilant
Synonyms:	CORT125281;CORT-125281
SMILES:	C([C@]12[C@@]([H])(CC3N(C4=CC=C(F)C=C4)N=CC=3C1)CCN(S(C1C=NN(C)N=1)(=O)=O)C2)(C1=NC=CC(C(F)(F)F)=C1)=O
Formula:	C₂₆H₂₃F₄N₇O₃S
M.Wt:	589.57
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Cat. No.	Product name	Field of application
DC40890	21-Acetoxypregna-1,4,9(11),16-tetraene-3,20-dione	21-Acetoxypregna-1,4,9(11),16-tetraene-3,20-dione is an intermediate of delta 9,11 steroids synthesis, for example, Vamorolone. The delta 9,11 steroids are modifications of glucocorticoids and has anti-inflammatory properties. The delta 9,11 steroids are agents for protection against cell damage (lipid peroxidation) and inhibition of neovascularization.
DC72900	HP210	HP210 is a selective glucocorticoid receptor modulator (SGRM). HP210 can inhibit the mRNA expression of IL-1β and IL-6. HP210 has the potential to study inflammation-related diseases.
DC71961	Nenocorilant	Nenocorilant (Relacorilant) is a potent, orally activity glucocorticoid receptor (GR) antagonist with Ki value of 0.15 nM. Nenocorilant has pro-apoptotic effects and improves potency combined with cytotoxic agent. Nenocorilant can be used for cancer research.
DC71960	Beclometasone dipropionate monohydrate	Beclometasone dipropionate monohydrate, the prodrug of Beclometasone, is an orally active and potent glucocorticoid recepter agonist. Beclometasone dipropionate monohydrate acts via a glucocorticoid receptor and suppresses inflammation and hyperproliferation. Beclometasone dipropionate monohydrate can be used for asthma .
DC71054	Hydrocortisone aceponate	Hydrocortisone aceponate (Hydrocortisone 17-propionate 21-acetate) is a potent topical glucocorticoid. Hydrocortisone aceponate can be used for various dermatoses research.
DC70396	Exicorilant	Exicorilant (CORT125281, CORT-125281) is a potent, selective glucocorticoid receptor (GR) antagonist, exhibits no cross-reactivity for the PR and AR receptors.
DC50229	Glucocorticoids receptor agonist 3	Glucocorticoids receptor agonist 3 is a potent agonist of glucocorticoids receptor. Glucocorticoids receptor agonist 3 is useful to research diseases, such as obesity, diabetes, and inflammation (extracted from patent WO2000066522A1, compound 345).
DC50228	Cortodoxone-d2	Cortodoxone-d2 (11-Deoxycortisol-d2) is the deuterium labeled Cortodoxone. Cortodoxone is a glucocorticoid steroid hormone that can be oxygenated to cortisol (Hydrocortisone).
DC50227	Cortodoxone-d5	Cortodoxone-d5 (11-Deoxycortisol-d5) is the deuterium labeled Cortodoxone.
DC50226	Hydrocortisone-d3	Hydrocortisone-d3 (Cortisol-d3) is the deuterium labeled Hydrocortisone. Hydrocortisone (Cortisol) is a steroid hormone or glucocorticoid secreted by the adrenal cortex.