GLP-1R modulator L7-028|CAS 2648317-95-5|DC Chemicals

Cas No.:	2648317-95-5
Chemical Name:	GLP-1R modulator L7-028
Synonyms:	AKOS040757936;CS-0254868;GLP-1R modulator L7-028;2648317-95-5;EX-A5912;HY-141842;MS-26570;Benzamide, 3-(cyclopentyloxy)-N-[3-(1-piperidinylcarbonyl)phenyl]-;DA-73759
SMILES:	O(C1C=CC=C(C(NC2=CC=CC(=C2)C(N2CCCCC2)=O)=O)C=1)C1CCCC1
Formula:	C₂₄H₂₈N₂O₃
M.Wt:	392.490726470947
Purity:	98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Cat. No.	Product name	Field of application
DC74600	Lotiglipron	Lotiglipron (PF-07081532) is an orally active GLP-1R agonist. It reduces glucose and body weight, and has the potential to be used in Type 2 diabetes mellitus (T2DM) research.
DC70577	LY3502970 (Orforglipron)	LY-3502970 (Orforglipron) is a potent, selective, orally active non-peptide agonist of glucagon-like peptide-1 (GLP-1) receptor.LY3502970 is a partial agonist, biased toward G protein activation over β-arrestin recruitment at the GLP-1R.
DC47635	GLP-1R modulator L7-028	GLP-1R modulator L7-028 is an allosteric modulator enhancing GLP-1 binding to GLP-1R via a transmembrane site (EC50 11.01 ± 2.73 μM).
DC46189	Teduglutide	Teduglutide (ALX-0600, Gattex, Revestive, TAK 633) is an analogue of human glucagon-like peptide-2 (GLP-2) and binds to the GLP-2 receptors. Teduglutide prolongs the intestinotrophic properties of GLP-2 in animal models.
DC45570	Tirzepatide (LY3298176)	Tirzepatide (LY3298176, GIP/GLP-1 RA, TZP) is a dual GIP/GLP-1 receptor agonist. Tirzepatide differentially induces internalization of the GIP and GLP-1 receptors with EC50 values of 18.2 nM and 18.1 nM, respectively.
DC45527	Avexitide	Avexitide (Exendin (9-39)) is a specific and competitive antagonist of glucagon-like peptide-1 (GLP-1) receptor.
DC10278	LGD-6972	LGD-6972 is a selective and orally active glucagon receptor antagonist. LGD-6972 has the potential for type 2 diabetes research.