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GSK2190915 sodium

Cat. No.: DC70142

Chemical Structure

1196070-26-4

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Field of application

A potent, selective FLAP inhibitor with binding IC50 of 2.6 nM; inhibits LTB4 synthesis following ionophore challenge in human whole blood with IC50 of 76 nM (5 h incubation); shows good selectivity over CYP3A4, 2C9, and 2D6; exhibits excellent preclinical toxicology, pharmacokinetics and oral bioactivity.

Chemicals Properties Biological activity Related products COA MSDS Datasheet

Cas No.:	1196070-26-4
Chemical Name:	GSK2190915 sodium
Synonyms:	GSK-2190915A;Fiboflapon sodium;AM-803 sodium
Formula:	C₃₈H₄₂N₃NaO₄S
M.Wt:	659.8126
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Cat. No.	Product name	Field of application
DC73518	MK-886	MK-886 (L-663,536) is a potent, selective and orally active inhibitor of 5-lipoxygenase-activating protein (FLAP) with IC50 of 30 nM.
DC70142	GSK2190915 sodium	A potent, selective FLAP inhibitor with binding IC50 of 2.6 nM; inhibits LTB4 synthesis following ionophore challenge in human whole blood with IC50 of 76 nM (5 h incubation); shows good selectivity over CYP3A4, 2C9, and 2D6; exhibits excellent preclinical toxicology, pharmacokinetics and oral bioactivity.

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.