GSK3004774|CAS 2138814-32-9|DC Chemicals

Cas No.:	2138814-32-9
Chemical Name:	GSK3004774
Synonyms:	GSK 3004774;GSK-3004774
Formula:	C₃₂H₄₀N₄O₃
M.Wt:	528.697
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Cat. No.	Product name	Field of application
DC42449	SB-423562	SB-423562 is a short-acting calcium-sensing receptor (CaR) antagonist.
DC60813	NPS-2143(SB 262470A )	NPS-2143(SB 262470A ) is a selective potent calcium ion-sensing receptor antagonist with IC50 of 43 and 41 nM for cytoplasmic Ca2+ concentrations and parathyroid hormone secretion, respectively.
DC73385	(S)-AC-265347	(S)-AC-265347 is a potent, selective CaSR agonist and positive allosteric modulator (ago-PAM), 10- to 20-fold more potent than (R)-AC-265347.
DC70092	GSK3004774	GSK3004774 (GSK-3004774) is a potent, nonabsorbable, gastrointestinally-restricted agonist agonist of calcium-sensing receptor (CaSR) with pEC50 of 7.3.
DC48388	Upacicalcet sodium	Upacicalcet (sodium) is an intravenous calcimimetic agent. Upacicalcet suppresses excessive parathyroid hormone (PTH) secretion, thereby lowering blood PTH levels, by acting directly on parathyroid cell membrane calcium-sensing receptors. Upacicalcet can be used for researching the disease of secondary hyperparathyroidism (SHPT).