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Home > Inhibitors & Agonists > Nuclear Receptor/Transcription Factor > Keap1-Nrf2

HPPE

Cat. No.: DC70491 Featured

Chemical Structure

1325721-55-8

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Field of application

HPPE is a specific nonelectrophilic and physiological Bach1 inhibitor via heme-binding sites of Bach1 protein, derepresses Bach1-mediated repression.HPPE induces up-regulation of Hmox1 mRNA is mediated by Bach1 inhibition in vivo.

Chemicals Properties Biological activity Related products COA MSDS Datasheet

Cas No.:	1325721-55-8
Chemical Name:	1H-Benzimidazole-5-carboxamide, N-[2-(2-hydroxyethoxy)ethyl]-1-methyl-2-[[6-(trifluoromethyl)-2-benzothiazolyl]amino]-
Synonyms:	1H-Benzimidazole-5-carboxamide, N-[2-(2-hydroxyethoxy)ethyl]-1-methyl-2-[[6-(trifluoromethyl)-2-benzothiazolyl]amino]-
SMILES:	C1(NC2=NC3=CC=C(C(F)(F)F)C=C3S2)N(C)C2=CC=C(C(NCCOCCO)=O)C=C2N=1
Formula:	C₂₁H₂₀F₃N₅O₃S
M.Wt:	479.475413322449
Purity:	98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Cat. No.	Product name	Field of application
DC70491	HPPE	HPPE is a specific nonelectrophilic and physiological Bach1 inhibitor via heme-binding sites of Bach1 protein, derepresses Bach1-mediated repression.HPPE induces up-regulation of Hmox1 mRNA is mediated by Bach1 inhibition in vivo.
DC10282	ML385	ML385 is a novel and specific NRF2 inhibitor.

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.