hypocrellin A|cas 77029-83-5|Supplied by DC Chem

Cas No.:	77029-83-5
SMILES:	OC1=C2C(C(C([C@@H](C(C)=O)[C@@](C)(O)C3)=C1OC)=C(C3=C4OC)C5=C6C(OC)=CC(O)=C5C4=O)=C6C(OC)=CC2=O
Formula:	C₃₀H₂₆O₁₀
M.Wt:	546.52
Purity:	>98%, Standard References Grade
Sotrage:	4°C for 1 year, -20°C for more than 2 years

Description:

Hypocrellin A, a naturally occurring PKC inhibitor, has many biological and pharmacological properties, such as antitumour, antiviral, antibacterial, and antileishmanial activities. Hypocrellin A is a promising photosensitizer for anticancer photodynamic therapy (PDT)[1][2][3][4].

References:

[1]. Dang L, et al. Effects of hypocrellin A on expression of vascular endothelial growth factor and endothelin-1 in human umbilical endothelial cells. Am J Chin Med. 2007;35(4):713-23. [2]. Ma YJ, et al. Enhanced Production of Hypocrellin A in Submerged Cultures of Shiraia bambusicola by Red Light. Photochem Photobiol. 2019 May;95(3):812-822. [3]. Fehr MJ, et al. Roles of oxygen and photoinduced acidification in the light-dependent antiviral activity of hypocrellin A. Biochemistry. 1995 Dec 5;34(48):15845-8. [4]. Ma G, et al. Antimicrobial and antileishmanial activities of hypocrellins A and B. Antimicrob Agents Chemother. 2004 Nov;48(11):4450-2.

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