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Rentosertib

Cat. No.: DC74461 Featured

Chemical Structure

2828567-39-9

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Field of application

INS018_055 (INS018-055) a selective small-molecule TRAF2- and NCK-interacting kinase (TNIK) inhibitor with Kd value of 4.32 nM and IC50 of 31 nM, inhibits TGF-β-induced α-SMA protein expression in MRC-5 cells with IC50 of 27.14 nM.

Chemicals Properties Biological activity Related products COA MSDS Datasheet

Cas No.:	2828567-39-9
Chemical Name:	Rentosertib
Synonyms:	INS018-055; INS018055; INS018 055; ISM001-055; TNIK&MAP4K4-IN-2; compound 112; rentosertibum; rentosertib
SMILES:	O=C(C1=CN=C(C2=C(C3=CC=C(C=C3)F)N=CN2C(C)C)N1)NC4=CC=C(N5CCN(CC5)C)C=C4
Formula:	C₂₇H₃₂FN₇O
M.Wt:	489.6
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Cat. No.	Product name	Field of application
DC74461	Rentosertib	INS018_055 (INS018-055) a selective small-molecule TRAF2- and NCK-interacting kinase (TNIK) inhibitor with Kd value of 4.32 nM and IC50 of 31 nM, inhibits TGF-β-induced α-SMA protein expression in MRC-5 cells with IC50 of 27.14 nM.

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.