ITE|CAS 448906-42-1|DC Chemicals

Cas No.:	448906-42-1
Chemical Name:	ITE
Synonyms:	Methyl 2-(1H-indole-3-carbonyl)thiazole-4-carboxylate;ITE;2-(1H-Indol-3-ylcarbonyl)-4-thiazol ecarboxylic acid methyl ester;4-Thiazolecarboxylicacid, 2-(1H-indol-3-ylcarbonyl)-, methyl ester;methyl 2-(1H-indole-3-carbonyl)-1,3-thiazole-4-carboxylate;HMS3268G16;2-(1H-INDOL-3-YLCARBONYL)-4-THIAZOLECARBOXYLIC ACID METHYL ESTER;AK116400;AHR agonist;The endogeneous AHR ligand;Aryl hydrocarbon receptor ligand;BCP17758;6191AB;SB17198;NCGC0;FT-0732784;C75214;Q27164789;A22724;BRD-K60298136-001-01-7;NCGC00159529-01;BI166811;2-(1H-Indol-3-ylcarbonyl)-4-thiazolecarboxylicacidMethylester;CHEBI:93059;AKOS016010400;BDBM50506039;2-[1H-indol-3-yl(oxo)methyl]-4-thiazolecarboxylic acid methyl ester;HY-19317;DTXSID70405386;MFCD06411597;SCHEMBL422944;CS-5141;2-(1'H-Indole-3'-carbonyl)-thiazole-4-carboxylic acid;4-Thiazolecarboxylic acid, 2-(1H-indol-3-ylcarbonyl)-, methyl ester;CHEMBL1324296;AMY29062;NCGC00159529-02;NCGC00159529-03;EX-A1251;AS-55789;448906-42-1;methyl 2-(1H-indole-3-carbonyl)thiazole-4-carboxylate;DB-023618;2-(1H-Indol-3-ylcarbonyl)-4-thiazolecarboxylic Acid Methyl Ester; 2-(1'H-Indole-3'-carbonyl)thiazole-4-carboxylic Acid Methyl Ester;Methyl 2-(1H-indole-3-carbonyl)-1,3-thiazole-4-carboxylate
SMILES:	S1C([H])=C(C(=O)OC([H])([H])[H])N=C1C(C1=C([H])N([H])C2=C([H])C([H])=C([H])C([H])=C12)=O
Formula:	C₁₄H₁₀N₂O₃S
M.Wt:	286.3058
Purity:	98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Cat. No.	Product name	Field of application
DC73809	ITE	A endogenous ligand, potent aryl hydrocarbon receptor (AhR) agonist in vitro.
DC28934	VAF347	VAF347 is a cell permeable and highly affinity aryl hydrocarbon receptor (AhR) agonist and induces AhR signaling. VAF347 inhibits the development of CD14+CD11b+ monocytes from granulo-monocytic (GM stage) precursors. VAF347 has anti-inflammatory effects.
DC28914	AhR modulator-1	AhR modulator-1 (compound 6-MCDF) is a selective and orally active aryl hydrocarbon receptor (AhR) modulator. AhR modulator-1 inhibits metastasis, in part, by inhibiting prostatic VEGF production prior to tumor formation. AhR modulator-1 also possess anti-estrogenic properties in rat uterus.
DC11794	GNF-351	GNF-351 is a potent, pure aryl hydrocarbon receptor (AHR) antagonist (IC50=62 nM) devoid of partial agonist potential; antagonizes agonist and SAhRM-mediated suppression of SAA1, inhibit both DRE-dependent and -independent activity; decreases migration and invasion of HNSCC cells and prevents benzo[a]pyrene-mediated induction of the chemotherapy efflux protein ABCG2.
DC11530	Tapinarof (Benvitimod; GSK2894512)	Tapinarof (WBI-1001) is a natural aryl hydrocarbon receptor (AhR) agonist with an EC50 of 13 nM. Tapinarof resolves skin inflammation in mice.