KI-301690|CAS 2757924-20-0|DC Chemicals

Cat. No.	Product name	Field of application
DC11175	Dual DDR1 and DDR2 inhibitor 5n	Dual DDR1 and DDR2 inhibitor 5n is a highly potent and selective small molecule inhibitor targeting both Discoidin Domain Receptor 1 (DDR1) and Discoidin Domain Receptor 2 (DDR2). These receptors are receptor tyrosine kinases (RTKs) that play critical roles in cell proliferation, migration, and extracellular matrix (ECM) remodeling. Dysregulation of DDR1 and DDR2 has been implicated in various diseases, including cancer, fibrosis, and inflammation, making them attractive therapeutic targets.
DC10996	DDR inhibitor X	DDR inhibitor X is a potent discoidin domain receptor (DDR) inhibitor with IC50 of 3.3 nM for DDR2, and shows 53% inhibition on DDR1 at 1.5 nM..
DC74384	KI-301690	KI-301690 (KI 301690) is a novel potent, specific DDR1 inhibitor, synergized with gemcitabine to suppress the growth of pancreatic cancer cells.
DC70795	SR-302	SR-302 (SR302) is a potent, selective cell-active dual DDR/p38 inhibitor with IC50 of 23/18/125/196 nM for DDR1/DDR2/p38α/p38β, respectively.