L-Buthionine-(S,R)-sulfoximine hydrochloride|CAS |DC Chemicals

Cas No.:
Chemical Name:	L-Buthionine-(S,R)-sulfoximine hydrochloride
SMILES:	N[C@H](C(O)=O)CCS(CCCC)(=O)=N.[H]Cl
Formula:	C₈H₁₉ClN₂O₃S
M.Wt:	258.77
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Cat. No.	Product name	Field of application
DC47659	CuATSM	CuATSM is a highly potent radical-trapping antioxidant (RTA) and inhibitor of (phospho)lipid peroxidation, thereby accounting for its (their) ability to inhibit ferroptosis.
DC45550	L-Buthionine-(S,R)-sulfoximine hydrochloride	L-Buthionine-(S,R)-sulfoximine hydrochloride is a cell-permeable, potent, fast acting, orally active and irreversible inhibitor of g-glutamylcysteine synthetase and depletes cellular glutathione levels. The IC50 value of L-Buthionine-(S,R)-sulfoximine on melanoma, breast and ovarian tumor specimens are 1.9 μM, 8.6 μM, and 29 μM, respectively.
DC28803	NBDHEX	NBDHEX is a potent glutathione S-transferase P1-1 (GSTP1-1) inhibitor. NBDHEX induces apoptosis of tumor cells. NBDHEX acts as an anticancer agent by inhibiting GSTs catalytic activity, avoiding inconvenience of the inhibitor extrusion from the cell by specific pumps and disrupting the interaction between the GSTP1-1 and key signaling effectors. NBDHEX can also act as late-phase autophagy inhibitor.