MAGL-IN-1|CAS 2324160-91-8|DC Chemicals

Cas No.:	2324160-91-8
Chemical Name:	Magl-IN-1
Synonyms:	MAGL-IN-1;(1-(2-fluoro-5-hydroxybenzoyl)piperidin-4-yl)(4-isopropylphenyl)methanone;MAGL Inhibitor Compound 23;BDBM50531972;[1-(2-fluoro-5-hydroxybenzoyl)piperidin-4-yl]-(4-propan-2-ylphenyl)methanone;CS-0086996;AKOS040733664;G16621;HY-111538;2324160-91-8;MS-25932;CHEMBL4536045
SMILES:	FC1=CC=C(C=C1C(N1CCC(C(C2C=CC(=CC=2)C(C)C)=O)CC1)=O)O
Formula:	C₂₂H₂₄FNO₃
M.Wt:	369.429269790649
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Cat. No.	Product name	Field of application
DC46532	MAGL-IN-4	MAGL-IN-4 is an orally active, selective and reversible monoacylglycerol lipase (MAGL) inhibitor with an IC50 of 6.2 nM. MAGL-IN-4 can penetrate the blood-brain barrier (BBB). MAGL-IN-4 enhances endocannabinoid signaling mostly by the increase in the level of 2-AG via selective MAGL inhibition in the brain.
DC44076	MAGL-IN-1	MAGL-IN-1 is a potent, selective, reversible and competitive inhibitor of MAGL, with an IC50 of 80 nM. MAGL-IN-1 exhibits anti-proliferative effects against human breast, colorectal, and ovarian cancer cells. MAGL-IN-1 blocks MAGL in cell-based as well as in vivo assays.