p97-IN-1|CAS 1863952-15-1|DC Chemicals

Cas No.:	1863952-15-1
Chemical Name:	1H-Indole-4-carboxamide, 2-methyl-1-[5,6,7,8-tetrahydro-4-[(phenylmethyl)amino]pyrido[2,3-d]pyrimidin-2-yl]-
Synonyms:	CB-5339
SMILES:	C1=C(C=CC=C1)CNC1NC(N2C(C)=CC3C(=CC=CC2=3)C(N)=O)=NC2C=1CCCN=2
Formula:	C₂₄H₂₄N₆O
M.Wt:	412.49
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:	p97-IN-1 is a potent p97 inhibitor with an IC50 <30 nM (WO2015109285A1, compound FF07).
References:	[1]. David Wustrow, et al. FUSED PYRIMIDINES AS INHIBITORS OF p97 COMPLEX. WO2015109285A1.

Cat. No.	Product name	Field of application
DC74320	OSSL_325096	OSSL_325096 is a novel potent small mlolecule p97/VCP inhibitor, suppresses cell proliferation and induces ER stress and apoptotic cell death in MM cell lines (IC50=0.1-0.5 uM).
DC70072	ML-241 hydrochloride	ML241 Hcl is a potent, selective and reversible AAA ATPase p97 inhibitor (IC50=100 nM).
DC48941	p97-IN-1	p97-IN-1 is a potent p97 inhibitor with an IC50 <30 nM (WO2015109285A1, compound FF07).