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Sunobinop

  Cat. No.:  DC47074   Featured
Chemical Structure
1126793-40-5
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More than 5000 active chemicals with high quality for research!
Field of application
Sunobinop (S 117957) is a modulator of the opioid receptor-like orphan receptor (ORL1).
Cas No.: 1126793-40-5
Chemical Name: Sunobinop
Synonyms: Sunobinop;I1X86U5474;V117957;4-[(1R,5S)-9-[(1S,5S)-3-bicyclo[3.3.1]nonanyl]-9-azabicyclo[3.3.1]nonan-3-yl]-3-oxoquinoxaline-2-carboxylic acid;Sunobinop [INN];Sunobinop [USAN];RSC117957;WHO 11537;2-Quinoxalinecarboxylic acid, 4-((3-endo)-9-(3-exo)-bicyclo(3.3.1)non-3-yl-9-azabicyclo(3.3.1)non-3-yl)-3,4-dihydro-3-oxo-;4-((1R,1'R,3R,3'R,5S,5'S)-9'-Aza(3,9'- bi(bicyclo(3.3.1)nonan))-3'-yl)-3-oxo-3,4- dihydroquinoxaline-2-carboxylic acid
SMILES: O=C1C(C(=O)O[H])=NC2=C([H])C([H])=C([H])C([H])=C2N1C1([H])C([H])([H])[C@]2([H])C([H])([H])C([H])([H])C([H])([H])[C@]([H])(C1([H])[H])N2C1([H])C([H])([H])[C@@]2([H])C([H])([H])C([H])([H])C([H])([H])[C@@]([H])(C2([H])[H])C1([H])[H]
Formula: C26H33N3O3
M.Wt: 435.5585
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Cat. No. Product name Field of application
DC47074 Sunobinop Sunobinop (S 117957) is a modulator of the opioid receptor-like orphan receptor (ORL1).
DC46693 DAMGO DAMGO (DAGO) is a potent and selective μ opioid receptor agonist with ki of 17 nM.
DC44976 LY2940094 tartrate LY2940094 (BTRX-246040) tartrate is a potent, brain penetrant, selective and orally available N/OFQ peptide (NOP) receptor antagonist with high affinity (Ki=0.105 nM) and antagonist potency (Kb=0.166 nM). LY2940094 tartrate reduces Ethanol self-administration and Ethanol seeking in animal models.
DC28780 LY2444296 LY2444296 is an orally bioavailable, high-affinity and selective short-acting kappa opioid receptor (KOPR) antagonist, with a Ki value of ∼1 nM. LY2444296 exhibits anti-anxiety like effects.
DC10290 PZM21 PZM21 is a potent and selective μ opioid receptor agonist with an EC50 of 1.8 nM.
DC9527 Methylnaltrexone (Bromide) Methylnaltrexone Bromide is a pheriphally-acting μ-opioid antagonist that acts on the gastrointestinal tract to decrease opioid-induced constipation.
DC9526 Meptazinol (hydrochloride) Meptazinol Hcl(WY-22811 Hcl) is a unique centrally active opioid analgesic.
DC7050 ADL5859 HCl ADL5859 agonizes δ-opioid receptor with a 1000-fold selectivity than µ- or κ-opioid receptor with Ki of 32 nM and 37 nM, respectively.ADL5859 displays weak inhibitory activity at the hERG channel with an IC50 of 78 μM. The EC50 of ADL5859 against δ opioid
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