Tavapadon|1643489-24-0|DC Chemicals

Cas No.:	1643489-24-0
Chemical Name:	Tavapadon
Synonyms:	Tavapadon;(Rac)-Tavapadon;PT4P8MJP8L;Tavapadon (USAN);Tavapadon [USAN];BCP32804;DB14899;D11431;(-)-1,5-dimethyl-6-(2-methyl-4-((3-(trifluoromethyl)pyridin-2-yl)oxy)phenyl)-2,4(1H,3H)-pyrimidinedione;2,4(1H,3H)-Pyrimidinedione, 1,5-dimethyl-6-(2-methyl-4-((3-(trifluoromethyl)-2-pyridinyl)oxy)phenyl)-, (-)-;1,5-dimethyl-6-[2-methyl-4-[3-(trifluoromethyl)pyridin-2-yl]oxyphenyl]pyrimidine-2,4-dione;DA-67955;PF-06649751;GTPL13372;UNII-PT4P8MJP8L;CVL-751;1,5-dimethyl-6-(2-methyl-4-{[3-(trifluoromethyl)pyridin-2-yl]oxy}phenyl)-3H-pyrimidine-2,4-dione;AC-36997;AKOS040742684;CS-0131271;1,5-dimethyl-6-[2-methyl-4-[3-(trifluoromethyl)pyridin-2-yl]oxy-phenyl]pyrimidine-2,4-dione;AKQXQLUNFKDZBN-UHFFFAOYSA-N;1643462-64-9;SCHEMBL16334991;DTXSID301337071;tavapadonum;1,5-dimethyl-6-[2-methyl-4-[[3-(trifluoromethyl)-2-pyridinyl]oxy]phenyl]-2,4(1H,3H)-pyrimidinedione;1,5-dimethyl-6-(2-methyl-4-((3-(trifluoromethyl)pyridin-2-yl)oxy)phenyl)-1,2,3,4-tetrahydropyrimidine-2,4-dione;1,5-Dimethyl-6-(2-methyl-4-((3-(trifluoromethyl)pyridin-2-yl)oxy)phenyl)pyrimidine-2,4(1H,3H)-dione;1,5-dimethyl-6-(2-methyl-4-{[3-(trifluoromethyl)pyridin-2-yl]oxy}phenyl)-1,2,3,4-tetrahydropyrimidine-2,4-dione;Tavapadon?;DB-186035;1643489-24-0;G17190;6-(4-(3-(Trifluoromethyl)pyridin-2-yloxy)-2-methylphenyl)-1,5-dimethylpyrimidine-2,4(1h,3h)-dione;Tavapadon (USAN/INN);PF-06649751;PF 06649751;PF-6649751;PF-06649751;PF06649751;PF 06649751;HY-119486A;86W;TAVAPADON [INN];(-)-1,5-DIMETHYL-6-(2-METHYL-4-((3-(TRIFLUOROMETHYL)-2-PYRIDINYL)OXY)PHENYL)-2,4(1H,3H)-PYRIMIDINEDIONE;CHEMBL3697617;(-)-1,5-Dimethyl-6-(2-methyl-4-((3-(trifluoromethyl)pyridin-2-yl)oxy)phenyl)pyrimidine-2,4(1H,3H)-dione;EX-A3416;MS-26523
SMILES:	FC(C1=CC=CN=C1OC1C=CC(=C(C)C=1)C1=C(C)C(NC(N1C)=O)=O)(F)F
Formula:	C₁₉H₁₆F₃N₃O₃
M.Wt:	391.343854904175
Purity:	98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:

Tavapadon (PF 6649751, PF-06649751) is an orally available dopamine D1 receptor partial agonist for treatment of Parkinson's disease. Parkinson Disease Discontinued

Cat. No.	Product name	Field of application
DC5015	Rotigotine Hydrochloride	Rotigotine is dopamine D2 and D3 receptor agonist. Ki values are 13 and 0.71 nM for D2 and D3 respectively. Rotigotine also has significant affinity for 5-HT1A and adrenergic α2B receptors. Rotigotine exhibits antiparkinsonian acitivity.
DC11103	Tavapadon	Tavapadon is a potent, orally-bioavailable, selective partial agonist of the dopamine D1 and D5 receptors.
DC8883	BP897	BP897 is a partially selective D3 dopamine receptor agonist.