TFC 007|CAS 927878-49-7|DC Chemicals

Cas No.:	927878-49-7
Chemical Name:	TFC 007
Synonyms:	5-Pyrimidinecarboxamide,N-[4-[4-(4-morpholinylcarbonyl)-1-piperidinyl]phenyl]-2-phenoxy-;TFC 007;SCHEMBL23195705;CHEMBL4238186;TFC007;N-[4-[4-(morpholine-4-carbonyl)piperidin-1-yl]phenyl]-2-phenoxypyrimidine-5-carboxamide;BDBM50463722;EX-A3539;AKOS025142049;DA-68093;927878-49-7;HY-110167;NCGC00387231-01;CS-0033029;GTPL11392;TFC-007;N-[4-[4-(4-Morpholinylcarbonyl)-1-piperidinyl]phenyl]-2-phenoxy-5-pyrimidinecarboxamide;N-(4-(4-(Morpholine-4-carbonyl)piperidin-1-yl)phenyl)-2-phenoxypyrimidine-5-carboxamide
SMILES:	C1CN(CCC1C(=O)N2CCOCC2)C3=CC=C(C=C3)NC(=O)C4=CN=C(N=C4)OC5=CC=CC=C5
Formula:	C₂₇H₂₉N₅O₄
M.Wt:	487.55026
Purity:	98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Cat. No.	Product name	Field of application
DC71123	TFC 007	TFC-007, a selective hematopoietic prostaglandin D synthase (H-PGDS) inhibitor, show high inhibitory activity against H-PGDS enzyme (IC50 value of 83 nM). TFC-007 can be used for composing H-PGDS degradation inducer PROTAC(H-PGDS)-1 (TFC-007 binds to H-PGDS, and Pomalidomide binds to cereblon).
DC28168	FPL 62064	FLP 62064 is a potent 5-lipoxygenase (5-LOX) and COX-2 dual inhibitor. FLP 62064 has potently anti-inflammatory activity.