ZINC20451377|CAS 2306303-35-3|DC Chemicals

Cas No.:	2306303-35-3
Chemical Name:	ZINC20451377
SMILES:	COC1=CC=C(/C=C/C(=O)N2CCC(OC3=CC(CN4CCN(CC5=CN=CC=C5)CC4)=CC=C3)CC2)C=C1
Formula:	C₃₂H₃₈N₄O₃
M.Wt:	526.681
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Cat. No.	Product name	Field of application
DC53050	ATI-2173	ATI-2173 is a novel liver-targeted molecule designed to deliver the 5′-monophosphate of clevudine for the treatment of chronic hepatitis B infection.
DC72983	ZINC20451377	ZINC20451377 is a small molecule that binds to hepatitis B surface antigen (HBsAg) with high affinity (Kd=65.3 nM), reduces HBsAg levels and HBV virion secretion in cell culture model for HBV.
DC72290	DVR-01	DVR-01 is a HBV inhibitor with EC50 values of 1.7 and 1.6 μM in AML12HBV10 and HepDES19 cells, respectively. DVR-01 shows antiviral activity against drug-resistant HBV mutants with EC50s of 2.403-3.273 μM. DVR-01 can be used for the research of HBV infection and related diseases.
DC47259	Inarigivir ammonium	Inarigivir (ORI-9020) ammonium is a dinucleotide antiviral drug which can significantly reduce liver HBV DNA in transgenic mice expressing hepatitis B virus. Inarigivir (ORI-9020) act as an RIG-I agonist to activate cellular innate immune responses.
DC47062	Bersacapavir	Bersacapavir is a novel Hepatitis B Virus capsid assembly modulator.
DC11296	GLP-26	GLP-26 is a novel potent HBV capsid modulator that reduces secreted HBeAg in HepNTCPDL cells transfected with HBV wild type with EC50 of 0.7 uM.