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Cat. No. Product Name Field of Application Chemical Structure
DC33300 L-765314 Featured
L-765,314 is a drug which acts as a potent and selective antagonist for the Alpha-1 adrenergic receptor subtype α1B. It has mainly been used to investigate the role of α1B receptors in the regulation of blood pressure.
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DC9802 23-hydroxy butulinic acid (23-HBA) Featured
23-hydroxy butulinic acid (23-HBA) is a potent angiogenesis inhibitor.
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DC22871 MS-402 Featured
MS402 is a BD1-selective BET BrD inhibitor with Kis of 77 nM, 718 nM, 110 nM, 200 nM, 83 nM, and 240 nM for BRD4(BD1), BRD4(BD2), BRD3(BD1), BRD3(BD2), BRD2(BD1) and BRD2(BD2), respectively. MS402 blocks Th17 cell differentiation and ameliorates colitis in mice.
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DC32382 Brassinazole Featured
Brassinazole is an inhibitor of brassinosteroid biosynthesis that has been developed in order to probe the myriad functions of brassinosteroids.
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DC31005 GRP-60367 Featured
GRP-60367 is a first-in-class direct-acting RABV inhibitor with EC50 from 2 to 52 nM (different host cell lines) that blocks RABV G protein-mediated viral entry.
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DC20155 Tegoprazan Featured
Tegoprazan, a potassium-competitive acid blocker, is a potent, oral active and highly selective inhibitor of gastric H+/K+-ATPase that could control gastric acid secretion and motility, with IC50 values ranging from 0.29-0.52 μM for porcine, canine, and human H+/K+-ATPases in vitro.
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DC10404 BIA 10-2474 Featured
BIA 10-2474 is an inhibitor of fatty acid amide hydrolase (FAAH) with IC50 values of 50 to 70mg/kg in various rat brain regions.
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DC23041 Isochlorogenic acid A Featured
3,5-Dicaffeoylquinic acid (3,5-DCQA) is a natural phenolic compound that has been found in L. japonica, I. kaushue, and other plants.It has antioxidant, anti-inflammatory, and antiviral biological activities.
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DC28671 DT2216 Featured
DT2216 is a selective B-cell lymphoma extra large (BCL-XL) proteolysis-targeting chimera (PROTAC). DT2216 targets BCL-XL to the Von Hippel-Lindau (VHL) E3 ligase for degradation. DT2216 inhibits various BCL-XL-dependent leukemia and cancer cells but considerably less toxic to platelets.
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DC10861 3BDO Featured
3BDO is a new mTOR activator which can also inhibit autophagy.
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DC39825 JC-1 Featured
JC-1 is a membrane-permeable cationic dye that is used to study mitochondrial integrity in the context of cellular apoptosis.
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DC12491 3-methyl toxoflavin Featured
3-methyl toxoflavin. Toxoflavin acts as a pH indicator, changing between yellow and colorless at pH 10.5.
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DC12664 3-pyridine toxoflavin Featured
3-pyridine toxoflavin is an impurity of toxoflavin.
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DC8245 4E1rcat Featured
4E1RCat is an inhibitor of protein translation that has been shown to prevent eIF4E:eIF4G and eIF4E:4E-BP1 interaction.
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DC10689 4P-PDOT Featured
4P-PDOT, also known as 4-phenyl-2- propionamidotetralin, is a MT2-receptor-specific antagonist. MT2 melatonin receptor may be a novel target for analgesic drug development.
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DC7592 4SC-202 Featured
4SC-202 is an orally bioavailable benzamide and inhibitor of human class I histone deacetylases (HDACs) isoenzymes 1, 2 and 3, with potential antineoplastic activity. HDAC inhibitor 4SC-202 selectively binds to and inhibits class I HDACs leading to an acc
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DC10877 5,3-AB-CHMFUPPYCA Featured
5,3-AB-CHMFUPPYCA is an analytical reference standard that is structurally classified as a synthetic cannabinoid.
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DC9371 5-FAM SE Featured
5-FAM SE is a single isomer, it is one of the most popular green fluorescent reagents used for labeling peptides, proteins and nucleotides.
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DC9372 6-FAM SE Featured
6-FAM SE is another isomer of carboxyfluorescein.
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DC10854 6-MITC Featured
6-MITC is an inhibitor of viability of both PANC-1 and BxPC-3 cells. It also acts as an inhibitor of the expression of CSC signaling molecule SOX2.
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DC7925 GTPL-5846 (6-OAU) Featured
6-OAU(GTPL5846; 6-n-octylaminouracil) is a surrogate agonist of GPR84; activates human GPR84 in the presence of Gqi5 chimera in HEK293 cells with an EC50 of 105 nM in the PI assay.
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DC10855 7-Epi 10-Desacetyl Paclitaxel Featured
7-Epi 10-Desacetyl Paclitaxel is a paclitaxel impurity. The compound, originally isolated from Taxus yunnanensis, has shown potential growth inhibitory activities against human cancer cells.
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DC10856 7-Epipaclitaxel Featured
7-epi-Taxol is a paclitaxel binds to tubulin, interfering with the normal function of microtubule.
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DC10537 8-OH-DPAT Featured
8-OH-DPAT is a research chemical of the aminotetralin chemical class and has been widely used to study the function of the 5-HT1A receptor.
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DC8020 A77-01 Featured
A 77-01 is a potent inhibitor of TGF-β type I receptor superfamily activin-like kinase ALK5 with IC50 of 25 nM.
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DC22345 Penthiopyrad Featured
A carboxamide fungicide used to control a broad spectrum of diseases on large variety of corps.
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DC34093 EGFR inhibitor(YUN27078) Featured
YUN27078, also known as EGFR inhibitor, is an EGFR inhibitor. It directly depolymerizes microtubules and is used as a chemical probe to investigate both the EGFR pathway and microtubule dynamics. YUN27078 hax CAS#879127-07-8, no formal name For the convenience of scientific communication, we named it as YUN27078 (combined from Inchi key plus CAS#) according to Hodoodo Chemical Nomenclature
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DC39826 Homo-PROTAC cereblon degrader 1 Featured
Homo-PROTAC cereblon degrader 1, is a cereblon degrader.
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DC39235 Fmoc-Val-Ala-PAB-OH Featured
Fmoc-Val-Ala-PAB-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
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DC5041 DCC-2036 (Rebastinib) Featured
DCC-2036 is a conformational control Bcr-Abl inhibitor for Abl1(WT) and Abl1(T315I) with IC50 of 0.8 nM and 4 nM, also inhibits SRC, LYN, FGR, HCK, KDR, FLT3, and Tie-2, and low activity to seen towards c-Kit. Phase 1/2.
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