VU0418506 (VU 0418506) is a potent and selective mGlu4 positive allosteric modulator (PAM) with EC50 of 68 nM (hmGlu4).

VCE-004.3 (VCE004.3) is a novel semi-synthetic cannabidiol derivative behaving as a dual PPARγ/CB2 agonist and CB1 receptor modulator, binds and activates PPARγ (IC50=3.5 uM) and CB2 receptors (pKi=6.69) and antagonizes CB1 receptor (pKi=5.61).

Valsartan is a nonpeptide angiotensin II AT1-receptor antagonist with an IC50 ranging from 39.5 to 116 μM. This in turn causes blood vessel dilation.

Vabicaserin hydrochloride is a 5-hydroxytryptamine 2C (5-HT2C) receptor-selective agonist with an EC50 of 8 nM.

UK 14,304 is a full α2-adrenergic receptor (α2-AR) agonist.

U-92016A is an agonist of the serotonin (5-HT) receptor subtype 5-HT1A (Ki = 0.4 nM).

Trifluoperazine Dihydrochloride is a potent dopamine D2 receptor inhibitor used as an antipsychotic and an antiemetic.

TP455 (TP-455) is a highly potent, selective A2A adenosine receptor inverse agonist with IC50 of 1.9 nM in cyclic AMP assays in hA2A CHO cells.

Tozadenant (SYN-115) is an adenosine A2A receptor antagonist.

Topiramate is an anticonvulsant that antagonizes GluR5 receptors and acts as a positive allosteric modulator of GABA receptor-mediated currents.

Tolterodine L-Tartrate is a muscarinic receptor antagonist that is active at all mAChR M subtypes. This compound blocks the opening of ion channels by acetylcholine, which in turn leads to muscle relaxation by blocking neuronal signaling.

TM30089 is a slective CRTH2 antagonist, displaying high antagonistic potency on mouse CRTH2 with low affinity to TP and many other prostanoid receptors including the related anaphylatoxin C3a and C5a receptors.

TIC10 isomer(ONC201 isomer) is an isomer of TIC10; TIC10 is a potent, orally active, and stable small molecule that transcriptionally induces TRAIL in a p53-independent manner and crosses the blood-brain barrier.

Thiothixene is a typical antipsychotic.1 It selectively binds to dopamine D2 over D1, D3, and D4 receptors (Kis = 0.417, 338, 186.2, and 363.1 nM, respectively).

Taranabant is a highly selective cannabinoid-1 (CB1) receptor inverse agonist.

Strontium Ranelate is a bone metabolism modulator that inhibits bone resorption while maintaining bone formation. Commonly used as an antiosteoporotic.

ST-836 Hcl is a dopamine receptor ligand; Antiparkinsonian agent.

Sotalol Hydrochloride is an adrenergic beta-antagonist that is used in the treatment of life-threatening arrhythmias.

SKF 82958 hydrobromide is a D1/D5 receptor full agonist.

Setiptiline(Org-8282) is a serotonin receptor antagonist.

Setiptiline is a serotonin receptor antagonist.

Seliforant (SENS-111, SENS111) is a novel potent, selective histamine H4 receptor antagonist..

SCH-527123 is a potent antagonist of both CXCR1 and CXCR2 with IC50 of 42 nM and 3 nM, respectively.

SCH 546738 is a novel, potent and non-competitive small molecule CXCR3 antagonist with Ki of 0.4 nM .

SB271046 Hcl is a potent, selective and orally active 5-HT6 receptor antagonist with pKi of 8.9.

SB 242084 is a potent and selective antagonist of 5-HT2C receptor.

S1p receptor agonist 1 is an S1P receptor agonist extracted from patent WO 2015039587 A1, compound example 2.

RS 17053 hydrochloride is a potent and selective α1A adrenoceptor antagonist, with a pKi value of 9.1 in native cell membrane and a pA2 value of 9.8 in functional assays.

Roxatidine Acetate Hydrochloride is a histamine H2-receptor antagonist used in ulcer treatment. This compound has been found to inhibit platelet function in vitro.

Rizatriptan Benzoate is a selective serotonin 5-HTID receptor agonist which is structurally derived from tryptamine.