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Home > Inhibitors & Agonists > Metabolic Enzyme/Protease

Metabolic Enzyme/Protease

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Cat. No. Product Name Field of Application Chemical Structure
DC42113 Sulcatone
Sulcatone is an endogenous metabolite.
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DC42112 D-Asparagine
D-Asparagine (H-D-Asn-OH) is a competitive inhibitor of L-Asparagine hydrolysis with a Ki value of 0.24 mM. D-Asparagine is a source of nitrogen for yeast strains. D-Asparagine is a good substrate for the external yeast asparaginase but is a poor substrate for the internal enzyme.
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DC42106 Dibenzyl disulfide
Dibenzyl disulfide is an endogenous metabolite.
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DC42103 H-Val-Tyr-OH
H-Val-Tyr-OH is an endogenous metabolite.
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DC42095 HMMNI
HMMNI (Hydroxy dimetridazole) is a hydroxy metabolite of Dimetridazole. Dimetridazole is a nitroimidazole class drug that combats protozoan infections.
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DC42094 3-Hydroxy-4-aminopyridine
3-Hydroxy-4-aminopyridine is an endogenous metabolite.
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DC42093 2-Hydroxy-4-methylbenzaldehyde
2-Hydroxy-4-methylbenzaldehyde is an endogenous metabolite.
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DC42092 Methyl 3-phenylpropanoate
Methyl 3-phenylpropanoate is an endogenous metabolite.
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DC42091 2,4-Dihydroxybenzaldehyde
2,4-Dihydroxybenzaldehyde is an endogenous metabolite.
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DC42090 1,2-Cyclohexanedione
1,2-Cyclohexanedione is an endogenous metabolite.
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DC42089 m-Anisaldehyde
m-Anisaldehyde is an endogenous metabolite.
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DC42086 2,6-Dimethylhydroquinone
2,6-Dimethylhydroquinone is an endogenous metabolite.
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DC42082 2-Bromo-4'-hydroxyacetophenone
2-Bromo-4'-hydroxyacetophenone a PTP1B inhibitor, with a Ki of 42 μM.
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DC42081 4-Carboxypyrazole
4-Carboxypyrazole is an endogenous metabolite.
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DC42080 D-Allothreonine
D-Allothreonine is the D type stereoisomer of Allothreonine. D-Allothreonine is a peptido-lipid derived from bacteria. D-Allothreonine, amide-linked to the D-galacturonic acid, is also a constituent in the polysaccharide.
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DC42000 Cathepsin D and E FRET Substrate
Cathepsin D and E FRET Substrate is a fluorogenic substrate for cathepsins D and E and not for B, H or L. The cleavage occurs at the Phe-Phe amide bond resul. Cathepsin D and E FRET Substrate is a valuable tool for routine assays and for mechanistic studies on cathepsins E and D.
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DC41904 Cecropin P1, porcine
Cecropin P1, porcine is an antibacterial peptide originally identified in moths (Hyalophora cecropia) and later in pig intestine.
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DC41903 Defensin HNP-2 human
Defensin HNP-2 human is an endogenous antibiotic peptide and monocyte chemotactic peptide produced by human neutrophils.
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DC41902 Defensin HNP-1 human
Defensin HNP-1 human is a Human neutrophil peptides (HNPs), involved in endothelial cell dysfunction at the time of early atherosclerotic development.Defensin HNP-1 human can regulate the growth of atherosclerosis.
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DC41883 Atrial natriuretic factor (1-28) (human, porcine)
Atrial natriuretic factor (1-28) (human, porcine) (Atrial natriuretic peptide (1-28)) is an endogenous peptide produced by the heart, involved in blood pressure regulation. Atrial natriuretic factor (1-28) (human, porcine) produces natriuresis, diuresis and vasorelaxation in vivo.
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DC41855 [pTyr5] EGFR (988-993) (TFA)
[pTyr5] EGFR (988-993) TFA is derived from the autophosphorylation site (Tyr992) of epidermal growth factor receptor (EGFR 988-993). [pTyr5] EGFR (988-993) TFA is often complexed with the catalytically inactive protein-tyrosine phosphate 1B (PTP1B).
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DC41852 CTTHWGFTLC, CYCLIC TFA
CTTHWGFTLC, CYCLIC TFA is a cyclic peptide inhibitor for matrix metalloproteinases MMP-2 and MMP-9. The IC50 value for MMP-9 is ~8 μM.
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DC41687 Calcineurin autoinhibitory peptide TFA
Calcineurin autoinhibitory peptide TFA is a selective inhibitor of Ca2+/calmodulin-dependent protein phosphatase (calcineurin), with an IC50 of ~10 μM. Calcineurin autoinhibitory peptide TFA could protect neurons from excitatory neuronal death.
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DC41686 Calcineurin autoinhibitory peptide
Calcineurin autoinhibitory peptide is a selective inhibitor of Ca2+/calmodulin-dependent protein phosphatase (calcineurin), with an IC50 of ~10 μM. Calcineurin autoinhibitory peptide could protect neurons from excitatory neuronal death.
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DC41630 Guanylin(human) TFA
Guanylin(human) TFA, a 15-amino acid peptide, is an endogenous intestinal guanylate cyclase activator. Guanylin(human) TFA is mainly found in gastrointestinal tract which regulates electrolytead water transport in intestinal and renal epithelia through cyclic GMP-dependent mechanism.
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DC41629 Guanylin(human)
Guanylin(human), a 15-amino acid peptide, is an endogenous intestinal guanylate cyclase activator. Guanylin(human) is mainly found in gastrointestinal tract which regulates electrolytead water transport in intestinal and renal epithelia through cyclic GMP-dependent mechanism.
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DC41557 Enterostatin(human,mouse,rat) TFA
Enterostatin (human,mouse,rat) TFA is a pentapeptide mainly formed in the intestine by the cleavage of secreted pancreatic procolipase. Enterostatin ?selectively reduces fat intake, bodyweight, and body fat in vivo.
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DC41526 Melittin TFA
Melittin TFA is a PLA2 activator, stimulates the activity of the low molecular weight PLA2, while it does not the increase activity of the high molecular weight PLA2.
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DC41489 Kushenol B
Kushenol B is an isoprenoid flavonoid isolated from S. flavescens, has antimicrobial, anti-inflammatory and antioxidant activities. Kushenol B has inhibitory activity against cAMP phosphodiesterase (PDE), with an IC50 of 31 μM.
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DC41485 Orotidine 5′-monophosphate
Orotidine 5′-monophosphate is a pyrimidine ribonucleoside and plays a role as an endogenous metabolite of human, E. coli or mouse. Orotidine 5′-monophosphate is an intermediate in the biosynthesis of?uridine monophosphate (UMP). Orotidine 5′-monophosphate can be used for the study of mechanism of orotidine 5′-monophosphate decarboxylase.
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