Decyl glucoside synthesized by direct glucosidation of d-glucose over zeolite catalysts has estrogenicity. It is non-endocrine disruptive surfactant.

Amantanium bromide is a quaternary ammonium compound, which is used as an antiseptic/disinfectant for therapeutic fuction.

Declenperon acts as a reagent for antimalarial drug lead identification. The are also used in the chemical development of selective and specific serotonin S2-antagonists.

Dechloro trazodone is an antipsychotic with potential use as a schizophrenia agent. Trazodone impurity B.

Pentyl decanoate is a biochemical.

Tricaprin is used to construct solid lipid nanoparticles (SLNs) as delivery system for bromocriptine (B682600, Mesylate salt). It is also used in cationic SLNs to enhance p53 tumor suppressor gene transfer to lung cancer cells.

Deanol bitartrate is an antidepressive agent that has also been used in the treatment of movement disorders. The mechanism of action is not well understood.

DDD (analytical) is a biochemical.

Diazoacetic ester is also known as Ethyl Diazoacetate. Ethyl Diazoacetate is used in the synthesis of Arteludovicinolide A as well as pyrimidoazepine analogs as seritonin 5-HT2A/C receptor ligands for treatment of obesity. This compound contains solvent for added stability.

Isocyclosporin A is a rearranged degradation product formed by acid treatment of cyclosporin A under aqueous and non-aqueous conditions.

CAY10734 is an agonist of sphingosine-1-phosphate receptor 1 (S1P1). It selectively binds S1P1 over S1P2, S1P3, and S1P4 receptors but does also bind S1P5 receptors in radioligand binding assays. CAY10734 reduces peripheral blood lymphocytes and increases graft survival in a rat skin allograft model combination with cyclosporin A (CsA).

OM173-αA is a quinone bacterial metabolite that inhibits the growth of the bacteria M. gallisepticum, M. pneumoniae, and S. aureus. OM173-αA also inhibits the growth of the plant pathogenic fungus P. oryzae and several species of Trichophyton.

Sorafenib N-oxide is an active metabolite of sorafenib (BAY 43-9006), an inhibitor of Raf-1, B-RAF, and receptor tyrosine kinases. Sorafenib N-oxide inhibits FLT3 that contains the internal tandem duplication mutation (FLT3-ITD) and inhibits proliferation of MV4-11 acute myeloid leukemia (AML) cells expressing FLT3-ITD. It is selective for AML cell lines containing FLT3-ITD over lines containing wild-type FLT3. Sorafenib N-oxide is also a linear-mixed inhibitor of the cytochrome P450 (CYP) isoform CYP3A4.

Neoaureothin is a bacterial metabolite and androgen receptor (AR) antagonist that inhibits binding of dihydrotestosterone (DHT) to ARs and inhibits DHT-induced expression of prostate-specific antigen in LNCaP cells. It also has nematocidal activity against the pine wood nematode B. xylophilus and increases survival of P. densiflora trees inoculated with B. xylophilus.

Cholesteryl palmitate is a cholesterol ester used to form a stable tear film to study amphiphilic block copolymers as surfactants for dry eyes. Cholesteryl palmitate levels in amniotic fluid are decreased in pregnancies in which infants later developed respiratory distress syndrome and in patients with well-controlled diabetes. Levels of cholesteryl palmitate are increased in bronchoalveolar lavage fluid (BALF) from patients with chronic interstitial pneumonia.

Dansyl chloride is a reactive probe for the derivatization of primary amines, including those on amino acids, peptides, and polyamines, for detection by HPLC. It has also been used for the derivatization of compounds containing phenol groups, such as steroids, for detection by MS/MS. Dansyl chloride is a fluorescent probe for proteins and enzymes. It displays excitation/emission maxima of 340/535 nm, respectively, in acetone.

Rebaudioside D is a natural non-caloric sweetener. It is a steviol glycoside metabolized by gut microbiota to steviol, a compound whose safety is widely studied.

NSC-207895 is an inhibitor of the p53-binding protein MDMX. NSC 207895 decreases the expression and protein levels of MDMX and increases the expression of the p53 target gene CDKN1 (p21). It also increases the expression of the pro-apoptotic genes PUMA, Bax, and PIG3. NSC 207895 induces apoptosis and decreases cell viability in MCF-7 cells in a p53-dependent manner. It also induces p53-independent apoptosis in wild-type, mutated, and truncated p53 Ewing sarcoma cell lines selectively over wild-type and p53-null osteosarcoma cells

Alaproclate HCl is a selective serotonin reuptake inhibitor (SSRI). It inhibits depletion of serotonin (5-HT) induced by 4-methyl-α-ethyl-m-tyramine in rat cerebral cortex, hippocampus, hypothalamus, and striatum. Alaproclate inhibits NMDA-evoked currents and depolarization-induced voltage-dependent potassium currents in rat hippocampal neurons.

trans-ε-Viniferin is a stilbene polyphenol and dimer of trans-resveratrol that has been found in various red wines. It induces disaggregation of aggregated amyloid-β (1-42) (Aβ42) fibrils and decreases Aβ42- and IL-1β-induced release of TNF-α and IL-6 in primary mouse neuron and astrocyte cocultures. trans-ε-Viniferin reduces cytotoxicity induced by truncated huntingtin (Htt) in PC12 cells. It also reduces production of reactive oxygen species (ROS), mitochondrial dysfunction, and PGC-1α depletion and increases protein levels and deacetylase activity of sirtuin 3 (SIRT3) in cells expressing mutant Htt. trans-ε-Viniferin inhibits calcium-activated chloride channel currents in HT-29 cells. In vivo, trans-ε-viniferin reduces rotavirus-induced secretory diarrhea in mice without affecting the rotaviral infection. Dietary administration of trans-ε-viniferin reduces hepatic triglyceride accumulation and body weight increases in a mouse model of diet-induced obesity.

Aminomethyltrioxsalen hydrochloride is a psoralen compound DNA intercalator used to inactivate DNA and RNA viruses, including HIV-1, by nucleic acid cross-linking followed by UV irradiation.

Ipidacrine is a ring-constricted derivative of tacrine (Cognex) and a reversible acetylcholinesterase inhibitor used in memory disorders. Ipidacrine directly stimulates impulse transmission in the central nervous system and neuromuscular synapses by blocking membrane potassium channels. Ipidacrine enhances not only choline, but also adrenaline, serotonin, histamine, and oxytocin effects on smooth muscle.

Algestone is a synthetic progestational dihydroxy derivative of Progesterone. The acetonide group possesses anti-inflammatory properties.

Chloropyramine hydrochloride may be useful in the treatment of invasive breast cancer.

Tyramine hydrochloride is an indirect sympathomimetic. Tyramine does not directly activate adrenergic receptors, but it can serve as a substrate for adrenergic uptake systems and monoamine oxidase, so it prolongs the actions of adrenergic transmitters. It also provokes transmitter release from adrenergic terminals. Tyramine may be a neurotransmitter in some invertebrate nervous systems.

Ibacitabine is an antiviral drug.

Zoxazolamine is a uricosuric and muscle relaxant of which the mechanism of action is not well understood.

Tylvalosin is an antibacterial drug.

Penicillin G procaine is a semisynthetic antibiotic prepared by combining penicillin G with Procaine.

Adrenone hydrochloride displays antineoplastic activity and has been shown to inhibit growth of Ehrlich ascites tumors in mice.