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Novel inhibitors

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Cat. No. Product Name Field of Application Chemical Structure
DC35222 Bromo-PEG4-bromide
Bromo-PEG4-bromide is a PEG derivative containing two bromide groups. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions. The hydrophilic PEG spacer increases solubility in aqueous media.
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DC35211 Bromo-PEG3-alcohol
Bromo-PEG3-alcohol is a PEG derivative containing a bromide group and a terminal hydroxyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions. The hydroxyl group enables further derivatization or replacement with other reactive functional groups.
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DC35210 Bromo-PEG2-alcohol
Bromo-PEG2-alcohol is a PEG derivative containing a bromide group and a terminal hydroxyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions. The hydroxyl group enables further derivatization or replacement with other reactive functional groups.
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DC35021 Benzyl-PEG6-alcohol
Benzyl-PEG6-alcohol is a Benzyl PEG Linker. PEG Linkers may be useful in the development of antibody drug conjugates and drug delivery methods.
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DC34979 Aminooxy-PEG2-methane
Aminooxy-PEG2-methane is a PEG derivative containing an aminooxy group and a methane group. The aminooxy group can be used in bioconjugation. It reacts with an aldehyde to form an oxime bond. If a reductant is used, it will form a hydroxylamine linkage. PEG Linkers may be useful in the development of antibody drug conjugates and drug delivery methods.
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DC34931 m-PEG5-amine
m-PEG5-amine is a PEG derivative containing an amino group. The amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. PEG Linkers may be useful in the development of antibody drug conjugates.
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DC34772 Propargyl-PEG1-acid
Propargyl-PEG1-acid is a PEG derivative containing a propargyl group with a terminal carboxylic acid. The terminal carboxylic acid can reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond. The propargyl group can be reacted with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield a stable triazole linkage.
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DC34755 DCC Crosslinker
DCC Crosslinker, N,N'-dicyclohexylcarbodiimide, is a zero-length crosslinker that is often employed in peptide synthesis and organic synthesis. DCC's carbodiimide is useful for coupling amines and carboxylates without the insertion of spacer atoms. DCC crosslinker is commonly used in the synthesis of active ester-containing reagents.
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DC34747 DSP Crosslinker
DSP Crosslinker, also known as DTSSP Crosslinker, is a homobifunctional and cleavable crosslinker that is cell membrane permeable. DSP crosslinker has amine-reactive N-hydroxysuccinimide (NHS) esters at both ends of a cleavable, 8-atom (12.0 angstrom) spacer arm, and DSP cross links occur via these NHS esters.
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DC34723 NSC 10441
Acid Orange 6 is an orange dye.
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DC34704 Acexamic acid
Acexamic acid is wound-healing agent and analgesic composed of plasmutan. Acexamic acid is used to avoid pulmonary fibrosis in adult respiratory distress syndrome, but may cause complications including hypercalcemia and hypernatremia.
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DC34690 Sulfaguanidine
Sulfaguanidine is a sulfanilamide antimicrobial agent that is used to treat enteric infections. It functions by blocking the production of folic acid, to act as an antibiotic. It is active against Gram positive bacteria and Gram negative bacteria.
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DC34685 Parathion
Parathion is a highly toxic cholinesterase inhibitor that is used as an acaricide and as an insecticide.
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DC34670 TEPA
TEPA is an insect chemosterilant and an antineoplastic agent. It inhibits carcinoma growth.
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DC34669 Furalaxyl
Furalaxyl is an acylamino chiral fungicide.
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DC34668 Sulfacarbamide
Sulfacarbamide is an antimicrobial agent that has been investigated as a therapeutic biochemical for diabetes treatment. It may lower blood sugar.
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DC34664 Zimelidine
Zimelidine is a serotonin uptake inhibitor formerly used for depression, but was withdrawn worldwide because of the risk of Gullain-Barre syndrome associated with its use.
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DC34663 Narasin
Narasin is a novel agent that inhibits dengue virus replication in vitro through non-cytotoxic mechanisms, thus indicating its potential to be further developed as a therapeutic agent.It is used for the treatment of coccidiosis from a class of protozoa. It also triggers phospholipid scrambling of the erythrocyte cell membrane, an effect partially dependent on Ca2+ entry. It has been shown to foster apoptosis of tumor cells.
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DC34659 Pargyline
Pargyline is an irreversible selective monoamine oxidase (MAO)-B inhibitor drugwith antihypertensive properties. Pargyline has been found to bind with high affinity to the I2 imidazoline receptor (an allosteric site on the MAO enzyme).
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DC34644 Chlorphenoxamine Hydrochloride
Chlorphenoxamine HCl is an antihistaminic agent which reverses multidrug resistance in L1210 tumor cells.
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DC34622 Gentamicin X2 Sulfate
Gentamicin X2 Sulfate is a potent premature stop codon readthrough molecule and the common precursor of the gentamicin C antibiotic complex.
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DC34598 SCH-D
Vicriviroc Malate is a potent, highly selective, and orally bioavailable CCR5 antagonist.
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DC34541 Norfluoxetine hydrochloride
Norfluoxetine hydrochloride is an active metabolite of fluoxetine.
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DC34345 MP265
MP265 is an inhibitor of MreB polymerization.
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DC34312 NSC-65381
Cellocidin is a potent growth inhibitor for gammaherpesvirus-associated B-lymphomas that acts through activation of both the NF-κB and c-Myc-mediated signaling pathways.
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DC34285 GSNO
GSNO is an endogenous transnitrosation donor involved in S-nitrosation of a variety of cellular proteins. It acts by regulating diverse protein functions
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DC34267 NP-313
NP-313 is an antithrombotic agent with dual inhibition of thromboxane A2 synthesis and calcium entry.
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DC34230 5-Methylcytosine
5-Methylcytosine is a methylated cytosine. It acts as a ligand of the hDNMT1.
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DC34210 Cytidine 5'-diphosphate disodium
Cytidine 5'-diphosphate disodium is a substrate of CDP (nucleoside diphosphate) kinase (2.7.4.6). It has been shown to produce CTP in support of DNA and RNA biosynthesis and of ribonucleotide reductase to produce dCMP.
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DC34194 Sodium Oxamate
Sodium Oxamate is an LDH inhibitor. It inhibits L(+)-lactate dehydrogenase and derails the entire gluconeogenic pathway.
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