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Cat. No. Product Name Field of Application Chemical Structure
DC36652 1-fluoro-Decane
Decane, 1-fluoro- is a biochemical.
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DC36624 Cyclohexene
Cyclohexene, decafluoro- is also known as Perfluorocyclohexene. Perfluorocycloalkene (PFCA) is a general class of fluorocarbon compounds comprising many commercially available perfluorocyclo-olefins including hexafluorocyclobutene (or perfluorocyclobutene), octafluorocyclopentene (or perfluorocyclopentene ) and decafluorocyclohexene (or perfluorocyclohexene ). Perfluorocycloalkene is a cycloalkene with no aromatic character, and has only carbon and fluorine, but no hydrogen.
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DC36623 Perfluoro(1,3-dimethylcyclohexane)
Perfluoro-1,3-dimethylcyclohexane is perfluorinated branched cyclohexane used as a synthesis reagent for amorphous fluorocarbon film preparation by plasma polymerization, and for hydroformylation of linear terminal alkenes. As a chemically inert compound similar in properties to other perfluorocarbons, perfluoro-1,3-dimethylcyclohexane is an ideal tracer for other fluorocarbons as it can be detected at very low concentrations.
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DC36615 Diethylcarbamazine N-oxide
Diethylcarbamazine N-Oxide is a metabolite of Diethylcarbamazine (D443910) in mammals. Diethylcarbamazine N-Oxide shows more antifilarial activity than its parent compound.
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DC36592 T-2 triol
T-2 Mycotoxin is a trichothecene mycotoxin. It is a naturally occurring mold byproduct of Fusarium spp. fungus which is toxic to humans and animals.
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DC36587 Trimethylcolchicinic acid
Trimethylcolchicinic acid is an antimitotic agent disrupting microtubule action through the binding of tubulin and preventing polymerization. Has been shown to stimulate the intrinsic GTPase activity of tubulin. Induces apoptosis and activates the JNK/SAPK signals.
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DC36586 Trimethylcolchicinic acid methyl ether
Trimethylcolchicinic acid methyl ether, Antimitotic agent that intercepts microtubles by binding to tubulin and preventing its polymerization. Stimulates the intrinsic GTPase activity of tubulin. Induces apoptosis in several normal and tumor cell lines and activates the JNK/SAPK signal.
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DC36584 4-Desacetylvinblastine
4-Desacetylvinblastine is a a pro-drug of Vinblastine. An anti-tumor agent used in the treatment of prostate cancer.
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DC36564 Dapsone hydroxylamine
Dapsone hydroxylamine is the hydroxylamine derivative of the antibacterial dapspone (sc-203023), which is most commonly used as part of a multidrug therapy for the treatment of leprosy and as propchylaxis against pneumocystis pneumonia (PCP) in HIV patients. Dapsone hydroxylamine is a toxic metabolite that is responsible for the hemolytic anemia seen in patients following dapsone therapy.
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DC36519 Acid blue 3
Acid blue is also known as Patent Blue V, and is a dark bluish synthetic triphenylmethane dye used as a food coloring. As a food additive, it has E number E131. It is a sodium or calcium salt of [4-(α-(4-diethylaminophenyl)-5-hydroxy- 2,4-disulfophenylmethylidene)-2,5-cyclohexadien-1-ylidene] diethylammonium hydroxide inner salt. The color of the dye is pH-dependent. In aqueous solution, its color will vary from a deep blue in alkaline or weakly acidic medium to a yellow–orange in stronger acidic conditions. It is useful as a pH indicator for the range 0.8–3.0. The structure is also redox-sensitive, changing from a reduced yellow form to an oxidized red form in solution. The reduction potential of around 0.77 volts is similar to that of other triphenylmethane dyes. It is usable as a reversible redox indicator in some analytical methods.
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DC36502 Diazinon
Diazinon is a cholinesterase inhibitor that is used as an organothiophosphorus insecticide. Diazinon is active against approximately 120 species of insects and pests.1 It is metabolized into the cholinesterase inhibitors monothionotetraethyl pyrophosphate, dithionotetraethyl pyrophosphate, and triethylthionophosphate in vivo, which induce vomiting, fasciculation with muscular twitching, paralysis, and death (LD50 = 125 mg/kg) in rats. Diazinon induces formation of capsular adhesion in the kidneys and ulcer formation in the duodenum of dogs as well as mucosal erosion and serosal seepage in the intestines of mini pigs. Formulations containing diazinon were previously used as agricultural pesticides.
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DC36445 Dihydrotetrabenazine
Dihydrotetrabenazine (racemic) is an active metabolite of the vesicular monoamine transporter 2 (VMAT2) inhibitor tetrabenazine that is generated by hepatic carbonyl reductases. Dihydrotetrabenazine binds to mouse pons medulla, hypothalamus, and striatum and inhibits synaptic vesicular serotonin (5-HT) uptake. It also binds to human caudate nucleus, hippocampus, and substantia nigra pars compacta. Dihydrotetrabenazine stereoisomers bind to VMAT2 in rat striatum.
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DC36438 (+)-Ambuic Acid
Ambuic acid is a cyclohexanone that has phytopathogenic antifungal, quorum sensing inhibitory, and antibacterial activities. Ambuic acid inhibits the biosynthesis of cyclic peptides involved in quorum sensing, including gelatinase biosynthesis-activating pheromone (GBAP) in E. faecalis, autoinducing peptide I (AIP-I) in S. aureus, and LsrD698 and LsrD826 in L. innocua. It suppresses abcess formation in a mouse model of skin infection induced by methicillin-resistant S. aureus (MRSA) when administered at a dose of 5 μg and decreases the activity of the agr quorum sensing system in an in vivo reporter assay.
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DC36432 Quinolactactin A
Quinolactactin A is a quinolone fungal metabolite that inhibits TNF production induced by LPS in murine peritoneal macrophages. Quinolactacin A is a mixture of quinolactacin A1 and A2.
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DC36431 (-)-Rasfonin
(-)-Rasfonin is a fungal metabolite that inhibits proliferation of mouse splenocytes induced by concanavalin A and LPS.
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DC36388 NSC 613948
Nybomycin is a fungal metabolite with antibacterial activity. It is active against B. subtilis, B. cereus, B. mycoides, M. smegmatis, and K. pneumoniae. Nybomycin is also active against M. tuberculosis and M. bovis.
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DC36384 Sporidesmolide II
Sporidesmolide II is a cyclic depsipeptide.
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DC36375 Haloperidol Metabolite II
Reduced haloperidol is an active metabolite of haloperidol formed via reduction of haloperidol by ketone reductase. Reduced haloperidol inhibits radioligand binding to sigma-1 and dopamine D2 receptors and stimulates brain-derived neurotrophic factor (BDNF) secretion from CCF-SSTG1 and U87MG astrocytic glial cells. It also inhibits norepinephrine, dopamine, and serotonin (5-HT) reuptake.
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DC36373 ABTS
ABTS is a radical cation and a peroxidase substrate. It is used to assess antioxidant capacity in the Trolox equivalent antioxidant capacity (TEAC) assay. It is blue in the presence of sodium persulfate or metmyoglobin but decolorizes upon incubation with antioxidants, and the antioxidant capacity can be determined spectrophotometrically. ABTS has also been used as an enzyme substrate in ELISAs. Upon incubation with a peroxidase, it produces a soluble green product that can be quantified by colorimetric detection at 405 nm.
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DC36342 Boromycin
Boromycin is a boron-containing macrolide antibiotic that inhibits growth of B. subtilis and induces efflux of potassium ions from B. subtilis without affecting Na+/K±ATPase activity. It decreases the synthesis of protein, RNA, and DNA in B. subtilis, inhibits the growth of B. halodurans, and inhibits the futalosine pathway of menaquinone synthesis in B. halodurans. Boromycin reverses bleomycin-induced cell cycle arrest at the G2 phase in Jurkat cells. It inhibits replication of the HIV-1 strains LAV-1 and RF and the HIV-2 strain LAV-2 in MT-4 cells. It also inhibits replication of a clinical isolate of HIV-1, strain KK-1, in MT-4 cells and peripheral blood mononuclear cells.
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DC36275 GHK-Cu acetate
GHK-Cu acetate is a complex of the tripeptide Gly-His-Lys and a copper(II) ion that has wound healing and anti-inflammatory activities. It increases proliferation and the levels of collagen and secreted pro-matrix metalloproteinase-2 (MMP-2) in isolated human fibroblasts. GHK-Cu increases levels of collagen and glycosaminoglycans (GAGs) and the expression of decorin in the wound tissue of rats. It decreases LPS-induced increases in the levels of reactive oxygen species (ROS), IL-6, and TNF-α in RAW 264.7 cells when used at a concentration of 10 μM.3 GHK-Cu (10 μg/g) prevents LPS-induced decreases in lung superoxide dismutase (SOD) activity and glutathione (GSH) levels and reduces LPS-induced increases in the number of cells and the level of total protein in bronchoalveolar lavage fluid (BALF) in a mouse model of acute lung injury.
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DC36245 (E)-Astringin
Astringin is a phenolic stilbene glucoside that has antioxidant and antineoplastic activities. It scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH) radicals and inhibits cupric ion-induced lipid peroxidation of human LDL. Astringin inhibits development of preneoplastic lesions induced by 7,12-dimethylbenz(a)anthracene (DMBA) in mouse mammary glands.
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DC36233 Aminopyrazine carboxamide
Aminopyrazine carboxamide is a pyrazolone with analgesic, anti-inflammatory, and antipyretic properties.
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DC36207 alpha-Aminobenzylpenicilloic acid
Ampicilloic acid is a metabolite and impurity of the semi-synthetic antibiotic Ampicillin.
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DC36201 S-(3-Carboxypropyl)-L-cysteine
S-(3-Carboxypropyl)-L-cysteine is a thioether derivative of L-cysteine.
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DC36181 Antioxidant ZMB
Antioxidant ZMB is an antioxidant.
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DC36177 Alinidine
Alinidine is an anti-arrythmic that reduces heart-rate without blockade of beta-adrenoceptors.
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DC36161 Amidinomalonamide HCl
Amidinomalonamide hydrochloride is a chemical reagent used in the preparation of pyrimidooxazines used as DGAT1 inhibitors. This drug has potential use as an anti-obesity treatment.
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DC36157 AI3-61947
Berberine sulfate is a quaternary ammonium salt from the protoberberine group of benzylisoquinoline alkaloids.
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DC36154 AI3-60130
Nicarbazin is an equimolar complex of 4,4'-Dinitrocarbanilide and 2-Hydroxy-4,6-dimethylpyrimidine. It is used as a coccidiostat for poultry.
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