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Other Targets

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Cat. No. Product Name Field of Application Chemical Structure
DC36140 Aica ribonucleotide
AICAR, also known as AICA riboside, is a purine precursor with antineoplastic activity. It is important in treatment of metabolic diseases such as type 2 diabetes as well as possible treatment of various cancer types.
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DC36128 (+)-Febrifugine dihydrochloride
Febrifugine dihydrochloride is a biochemical with therapeutic activity regarding malaria, cancer, fibrosis and inflammatory diseases.
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DC36106 Adipostatin A
Adipostatin A is an inhibitor of glycerol-3-phosphate dehydrogenase (GPDH). It prevents triglyceride accumulation in 3T3-L1 cells and is cytotoxic against fibroblast carcinoma KB cell lines. It also shows larvicidal activity against A. aegypti.
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DC36071 Harmaline
Harmaline is a beta-carboline alkaloid isolated from seeds of PEGANUM. It is a psychoactive indole with stimulating activities achieved, in part, through inhibition of monoamine oxidases. Harmaline induces tremor in mice through the N-methyl-D-aspartate (NMDA) receptor, at which harmaline may act as an inverse agonist.
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DC36060 Antibiotic 379Y
Verrucarin A is an antibiotic which has been shown to inhibit proliferation of prostate cancer cells by inhibiting prosurvival Akt/NF-kB/mTOR signaling.
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DC36034 Aloesin
Aloesin is a competitive tyrosinase inhibitor. As an Aloe chromone, Aloesin has previously been formulated with an aloe polysaccharide to give a composition called Loesyn, where it showed significant impact in reducing glycosylated hemoglobin, fasting blood glucose, fructosamine and plasma insulin level in humans. This molecule has also been shown to modulate melanogenesis and have some anti-inflammatory effects in rats.
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DC36032 Aldrin-transdiol
Aldrin-transdiol is a metabolite of dieldrin. Aldrin-transdiol may be used in insecticides.
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DC35958 Ms-PEG3-Ms
Ms-PEG3-Ms is a PEG Linker.
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DC35927 [2-(Diethoxy-phosphorylamino)-ethyl]-phosphoramidic acid diethyl ester
[2-(Diethoxy-phosphorylamino)-ethyl]-phosphoramidic acid diethyl ester is a PEG Linker.
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DC35819 Mal-PEG2-alcohol
Mal-PEG2-alcohol is a PEG derivative containing a maleimide group and a hydroxyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.
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DC35730 Azido-PEG6-CH2CO2-t-Bu
Azido-PEG6-CH2CO2-t-Bu is a PEG derivative containing an azide group and a t-butyl ester. The hydrophilic PEG spacer increases solubility in aqueous media. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The t-butyl protected carboxyl group can be deprotected under acidic conditions.
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DC35622 Alkynyl Stearic Acid
Alkynyl Stearic Acid can be used to identify and characterize the post-translational acylation of proteins with powerful Click Chemistry.
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DC35566 m-PEG3-aldehyde
m-PEG3-aldehyde is a PEG derivative containing an aldehyde group. Aldehyde is reactive to hydrazide and aminooxy groups which are commonly used in biomolecular probes for labeling and crosslinking carbonyls (oxidized carbohydrates). The hydrophilic PEG spacer increases solubility in aqueous media.
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DC35492 PEG21
PEG21 is a PEG Linker. PEG Linkers may be useful in the development of antibody drug conjugates.
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DC35491 PEG18
PEG18 is a PEG Linker. PEG Linkers may be useful in the development of antibody drug conjugates.
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DC35485 Nonaethylene glycol
Nonaethylene glycol is a PEG Linker. PEG Linkers may be useful in the development of antibody drug conjugates.
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DC35450 Azide-PEG8-alcohol
Azide-PEG8-alcohol is a PEG derivative containing an azide group and a terminal hydroxyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The hydroxyl group enables further derivatization or replacement with other reactive functional groups.
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DC35254 Azidoethyl-SS-ethylazide
Azidoethyl-SS-ethylazide is a cleavable PEG Linker. PEG Linkers may be useful in the development of antibody drug conjugates.
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DC35221 Bromo-PEG3-bromide
Bromo-PEG3-bromide is a PEG derivative containing two bromide groups. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions. The hydrophilic PEG spacer increases solubility in aqueous media.
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DC35220 Bromo-PEG2-bromide
Bromo-PEG2-bromide is a PEG derivative containing two bromide groups. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions. The hydrophilic PEG spacer increases solubility in aqueous media.
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DC35067 Biotin-PEG2-Mal
Biotin-PEG2-Mal is a PEG derivative containing a biotin group and a maleimide group for labeling and crosslinking cysteines and other sulfhydryls. The maleimide group reacts specifically with sulfhydryl groups (at pH 6.5-7.5) to form a stable, irreversible thioether linkage. The hydrophilic PEG spacer increases solubility in aqueous media and increases membrane impermeability of the molecules conjugated to the biotin compound. It also helps to minimize steric hindrance involved with the binding to avidin molecules.
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DC34935 m-PEG24-amine
m-PEG24-amine is a PEG derivative containing an amino group. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. PEG Linkers may be useful in the development of antibody drug conjugates and drug delivery methods.
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DC34912 Amino-PEG7-amine
Amino-PEG7-amine is a PEG derivative containing two amino groups. The amino groups are reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. PEG Linkers may be useful in teh development of antibody drug conjugates.
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DC34760 NHS-Biotin
NHS-Biotin, Succinimidobiotin, is a primary amine reactive biotinylation reagent used in Biotin-Streptavidin binding reactions. The NHS-Biotin molecule is cell membrane permeable and can be used to covalently label intracellular proteins.
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DC34697 Phorate
Phorate is a cholinesterase inhibitor that is used as a broad-spectrum antibiotic. Its residues and metabolites may persist in soil, and may be toxic.
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DC34686 Temefos
Temefos is an organothiophosphate insecticide.
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DC34681 Oxamyl oxime
Oxamyl oxime is an agricultural chemical and pesticide.
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DC34673 Butralin
Butralin is a herbicide and plant-growth-controller.
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DC34646 Aminophylline
Aminophylline is an inhibitor of cAMP or cGMP phosphodiesterases, increasing levels of the second messenger cAMP or cGMP intracellularly, also acting as a CNS stimulant and exerts a positive chronotropic and inotropic effect on the heart.
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DC34642 Valerenic acid
Valerenic acid is a ?-subunit-dependent GABAA receptor modulator.
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