Isoflupredone Acetate is a topical anti-inflammatory corticosteroid.

Diflorasone Diacetate is a topical glucocorticoid with anti-inflammatory and immunosuppressive properties.

Arzanol is a positive modulator of brain glycogen phosphorylase.

4-Octyl Itaconate is a cell permeable activator of Nrf2 which inhibits LPS-induced increases in IL-1β mRNA, HIF-1α, and IL-10 in macrophages.

Sulindac Sulfide is a metabolite of sulindac.

gp130-agonist-2 is a brain penetrant gp130 agonist which protects against NMDA-induced toxicity and increases STAT3 phosphorylation.

L48H37 is a specific myeloid differentiation 2 (MD2) inhibitor.

Hemicholinium-3 is a competitive antagonist of CHT-mediated choline transport.

MMG-11 is a potent and selective dual inhibitor of TLR2/1 and TLR2/6 signaling with low cytotoxicity.

IMB-10 is an alphaMbeta2 integrin modulator, inhibiting leukocyte migration and recruitment in vitro and in vivo.

6-CFDA is a cell membranes permeatable non-fluorescent prodrug of 5-carboxyfluorescein. It shows strongly fluorescent to differentiate viable cells from apoptotic cells after being enzymatically hydrolyzed inside cells.

2002-H20 is an inhibitior of Aβ42-induced cytotoxicity. It acts by binding the Alzheimer's Aβ peptide and reducing its cytotoxicity.

Necrostatin-7 is a necroptosis inhibitor. It acts by inhibiting TNF-alpha-induced necroptosis in a FADD-deficient variant of human Jurkat T cells.

Phox-I2 is a second generation inhibitor of the p67phox interaction with Rac1, effective in suppressing reactive oxygen species production by human and murine neutrophils.

Norchlorcyclizine is a partially selective NPR-B inhibitor. It also acts as an inhibitor of human tyrosyl-DNA phosphodiesterase 1 (TDP1).

o-3M3FBS is a negative control for m-3M3FBS, an activator of phospholipase C (PLC).

Sulbutiamine is an antioxidant that act by inhibiting oxidative stress induced retinal ganglion cell death.

VU0071063 is an activator of Kir6.2/SUR1.

Diclofensine HCl is an antidepressant with equipotent inhibitive effects on the neuronal uptake of norepinephrine (NE), serotonin, and dopamine.

LUF5834 is a potent nonribose agonist, activating A2A and A2B adenosine receptor.

DCAI is an inhibitor of nuleotide exchange and nucleotide release. It acts by binding to the pocket adjacent to the Ras-SOS interface.

ITX3 is a nontoxic selective cell active inhibitor of the Trio/RhoG?/Rac1 pathway. It acts by validating RhoGEFs as druggable targets.

Pyrazofurin is an inhibitor of human dyskerin. It is also an antiviral agent.

TN-16 is a tubulin inhibitor.

1,4-DPCA is a potent and selective inhibitor of prolyl 4-hydroxylase.

Acetyl-L-carnitine is a stimulator of α-secretase activity and metabolism of amyloid precursor protein (APP). It has been shown to induce NF-κB-mediated upregulation of mGluR2 receptors, thereby exhibiting antidepressant, neuroprotective, analgesic, and antinociceptive activities.

SDM-25N HCl is a selective δ-opioid receptor antagonist.

4-CPI is an inhibitor of non-active site mutants of cytochrome P450 2B4.

PMSF is an inhibitor of serine proteases such as trypsin and chymotrypsin. It also inhibits cysteine proteases (reversible by reduced thiols) and mammalian acetylcholinesterase.

CCT036477 is a selective inhibitor of wingless-type MMTV integration site family (WNT)-dependent transcription. It reduces the transcriptional activity of the T-cell factor/lymphoid enhancer factor transcription factor family at the ?-catenin level.