BB-F-Yne is a cell-permeable derivative of the protein arginine diminase (PAD) inhibitor BB-Cl-amidine that contains an alkyne moiety for use in click chemistry reactions. BB-F-Yne inhibits PAD1-4 and has been used for labeling PADs in cell-free and cell-based assays, followed by click reactions with azide-modified TAMRA or biotin reporters.

Brevicompanine B is a fungal metabolite that has plant growth and circadian rhythm regulatory activity. Brevicompanine B inhibits primary root growth in Arabidopsis seedlings and disrupts the transcription of various genes involved in the regulation of plant circadian rhythm. It is active against P. falciparum.

Integracin B is a fungal metabolite and an inhibitor of HIV-1 integrase.

Zelkovamycin is a cyclic peptide antibiotic that inhibits growth of X. oryzae, P. oryzae, S. aureus, and A. laidlawii in a concentration-dependent manner.

Photoswitchable PAD inhibitor is a photoactivated protein arginine deiminase (PAD) inhibitor and a derivative of BB-Cl-amidine that contains an azobenzene photoswitch allowing optical control of PAD activity. Without photoactivation, it is a weak inhibitor of PAD2 and is less potent than BB-Cl-amidine in inhibiting citrulline production in vitro. It does not inhibit histone H3 citrullination in HEK293T cells overexpressing PAD2. However, it can rapidly be photoactivated with UV-A radiation to the more active cis-isomer, which is an irreversible, competitive inhibitor of histone H3 citrullination.

cis VH 032, amine dihydrochloride is a negative control for the functionalized VHL ligand VH 032, amine.

VH032 phenol - linker 2 is a functionalized von-Hippel-Lindau (VHL) protein ligand for PROTAC research and development. It incorporates an E3 ligase ligand plus an alkyl linker ready for conjugation to a target protein ligand.

Prostaglandin D synthase (hematopoietic-type) inhibitor F092 is an inhibitor of hematopoietic-type prostaglandin D synthase (H-PGDS).

LH1306 is an inhibitor of the interaction between programmed cell death 1 (PD-1) and its ligand PD-L1. It increases the activation of Jurkat cells expressing PD-1 in co-culture with U2OS or CHO cells expressing PD-L1.

MD001 is a dual agonist of peroxisome proliferator-activated receptor α (PPARα) and PPARγ. It binds to PPARα and PPARγ but does not bind to PPARβ/δ. It increases transcriptional activity of PPARα and PPARγ and glucose consumption. MD001 decreases levels of glucose, insulin, free fatty acids, triglycerides, LDL, alanine aminotransferase (ALT), and aspartate aminotransferase (AST) in blood and reduces the size and number of hepatic lipid droplets in diabetic db/db mice.

Pyrenophorol is a fungal metabolite that has been found in Alternaria and has diverse biological activities. It inhibits human topoisomerase II α when used at concentrations of 75 and 100 μM. It is active against S. cerevisiae (MIC = 4 μM) and M. violaceum. Pyrenophorol induces leaf necrosis and chlorophyll retention in wild oats when used at a concentration of 64 μM.

Thymohydroquinonee is a quinone that has been found in N. sativa seeds and has diverse biological activities. It scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH) free radicals and inhibits growth of A2780, OVCAR-8, CIS-A2780 ovarian cancer cells, and immortalized human ovarian epithelial cells. It is also active against P. falciparum in vitro.

CAY10735 is an anticancer compound that inhibits proliferation of melanoma, breast, pancreatic, and lung cancer cell lines by inhibiting the epithelial-to-mesenchymal transition (EMT).

AM-3102 is an OEA analog that stimulates PPARα transcriptional activity and prolongs feeding latency. It is resistant to enzymatic hydrolysis and is as potent as OEA in enhancing transcriptional activity of PPARα and reducing food intake in free-feeding rats. AM3102 demonstrates weak affinity for the central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors.

Nitrefazole is a nitroimidazole derivative with the ability to inhibit aldehyde dehydrogenase. This enzyme crucial to the metabolism of alcohol and is suitable for aldehyde dehydrogenase (ALDH) related research.

Canavanine sulfate is a biochemical with antimutagenic activity. This product has been shown to potentiate the cytotoxicity of doxorubicin and cisplatin in arginine deprived human cancer cells

Methylguanidine hydrochloride is a biochemical that can be used in the synthesis of biaryl derivatives which were evaluated as BACE1 inhibitors.

Melarsen oxide is a glutathione reductase inhibitor.

Pyrantel pamoate is a broad spectrum antinematodal anthelmintic.

Nifenazone is a drug used as an analgesic for a number of rheumatic conditions.

(2-pyridyldithio)-PEG2-t-butyl ester is a thiol PEG Linker.

(2-pyridyldithio)-PEG4-propargyl is a PEG Linker.

S-acetyl-PEG4-alcohol is a PEG Linker.

Methyltetrazine-PEG8-NHS ester is a PEG Linker.

Methyltetrazine-PEG8-acid is a PEG Linker

TCO-PEG4-biotin is a PEG Linker containing a TCO moeity.

Tos-PEG4-t-butyl ester is a PEG derivative containing a t-butyl ester and a tosyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The t-butyl protected carboxyl group can be deprotected under acidic conditions. The tosyl group is a very good leaving group for nucleophilic substitution reactions.

N-Mal-N-bis(PEG4-NH-Boc) is a branched PEG derivative with a terminal maleimide group and two terminal Boc protected amino groups. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol. The protected amines can be deprotected by acidic conditions.

N-Mal-N-bis(PEG2-NH-Boc) is a branched PEG derivative with a terminal maleimide group and two terminal Boc protected amino groups. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol. The protected amines can be deprotected by acidic conditions.

N-Mal-N-bis(PEG2-NHS ester) is a branched PEG derivative with a terminal maleimide group and two terminal NHS esters. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol. The NHS esters can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.