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Cat. No. Product Name Field of Application Chemical Structure
DC34999 t-Boc-Aminooxy-PEG2-alcohol
t-Boc-Aminooxy-PEG2-alcohol is a PEG derivative containing a Boc-protected aminooxy group and an alcohol group. The protected aminooxy can be deprotected under mild acidic conditions and then can be reacted with an aldehyde or ketone group to form a stable oxime linkage. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. Aminooxy PEG Linkers may be useful in bioconjugation experiments.
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DC34973 Aminooxy-PEG4-acid
Aminooxy-PEG4-acid is a PEG derivative containing an aminooxy group and a terminal carboxylic acid. The aminooxy group can be used in bioconjugation. It reacts with an aldehyde to form an oxime bond. If a reductant is used, it will form a hydroxylamine linkage. The terminal carboxylic acid can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond.
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DC34972 Aminooxy-PEG3-acid HCl
Aminooxy-PEG3-acid HCl salt is a PEG derivative containing an aminooxy group and a terminal carboxylic acid. The aminooxy group can be used in bioconjugation. The terminal carboxylic acid can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond.
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DC34965 Amino-Tri-(t-butoxycarbonylethoxymethyl)-methane
Amino-Tri-(t-butoxycarbonylethoxymethyl)-methane is a PEG derivative containing an amine group with three t-butyl esters. The amine groups is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The t-butyl protected carboxyl group can be deprotected under acidic conditions. PEG Linkers may be useful in the development of antibody drug conjugates.
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DC34963 NH-bis(PEG3-t-butyl ester)
NH-bis(PEG3-t-butyl ester) is a PEG derivative containing an amino group with two t-butyl esters. The amino groups is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The t-butyl protected carboxyl group can be deprotected under acidic conditions.
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DC34955 Amino-Tri-(carboxyethoxymethyl)-methane
Amino-Tri-(carboxyethoxymethyl)-methane is a PEG derivative containing an amino group with three terminal carboxylic acids. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The terminal carboxylic acids can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond. PEG Linkers may be useful in the development of antibody drug conjugates.
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DC34927 Amino-PEG3-sulfonic acid HCl
Amino-PEG3-sulfonic acid HCl salt is an amino PEG linker. PEG Amines contain an amino group which can react with acids, succinimidyl-active esters, or pentafluorophenyl esters for labeling, chemical modification, surface or particle modifications. PEG Linkers may also be useful for development of antibody drug conjugates.
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DC34924 Azido-PEG11-amine
Azido-PEG11-amine is a PEG derivative containing an amino group with an azide group. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. PEG Linkers may be useful in the development of antibody drug conjugates.
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DC34897 Amino-PEG10-t-butyl ester
Amino-PEG10-t-butyl ester is a PEG derivative containing an amino group with a t-butyl protected carboxyl group. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The t-butyl protected carboxyl group can be deprotected under acidic conditions. PEG Linkers may be useful in the development of antibody drug conjugates and drug delivery methods.
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DC34896 Amino-PEG9-t-butyl ester
Amino-PEG9-t-butyl ester is a PEG derivative containing an amino group with a t-butyl protected carboxyl group. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The t-butyl protected carboxyl group can be deprotected under acidic conditions. PEG Linkers may be useful for the development of antibody drug conjugates and drug delivery methods.
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DC34861 exo-BCN-PEG2-Boc-amine
exo-BCN-PEG2-Boc-amine is a PEG derivative containing a BCN group and a Boc-protected amine. The protected amine can be deprotected under mild acidic conditions. The BCN group can react with azide-tagged biomolecules. PEG Linkers and PEG derivatives may be useful in the development of antibody drug conjugates.
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DC34858 endo-BCN-PEG3-Boc-amine
endo-BCN-PEG3-Boc-amine is a PEG derivative containing a BCN group and a Boc-protected amine. The BCN group can react with azide-tagged biomolecules. PEG Linkers may be useful in the development of antibody drug conjugates and drug delivery methods.
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DC34857 endo-BCN-PEG2-alcohol
endo-BCN-PEG2-alcohol is a PEG derivative containing a BCN group and a hydroxyl group. The BCN group can react with azide-tagged biomolecules. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. PEG Linkers may be useful in the development of antibody drug conjugates and drug delivery methods.
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DC34855 endo-BCN-PEG4-t-butyl ester
endo-BCN-PEG4-t-butyl ester is a PEG derivative containing a BCN group and a t-butyl protected carboxyl group. The BCN group can react with azide-tagged biomolecules. The protected carboxyl group (COOH) prevents self coupling or polymerization under standard acid/amine or acid/hydroxyl coupling conditions. The protected acid can be deprotected by acidic or basic hydrolysis. PEG Linkers may be useful in the development of antibody drug conjugates.
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DC34850 endo-BCN-PEG4-NHS ester
endo-BCN-PEG4-NHS ester is a PEG derivative containing an NHS ester group and a BCN group. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. The BCN group can react with azide-tagged biomolecules. PEG Linkers may be useful in the development of antibody drug conjugates and drug delivery methods.
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DC34845 endo-BCN-PEG3-acid
endo-BCN-PEG3-acid is a PEG derivative containing a BCN group with a terminal carboxylic acid. The terminal carboxylic acid can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond. The BCN group can react with azide-tagged biomolecules. PEG Linkers may be useful in the development of antibody drug conjugates and in drug delivery.
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DC34836 Aminooxy-PEG3-propargyl
Aminooxy-PEG3-propargyl is a PEG derivative containing a propargyl group and an aminooxy group. The aminooxy group reacts with an aldehyde or ketone group to form a stable oxime linkage. The propargyl group can be reacted with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield a stable triazole linkage. PEG derivatives can be useful in antibody drug conjugates and drug delivery.
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DC34827 Propargyl-PEG4-sulfonic acid
Propargyl-PEG4-sulfonic acid is a PEG derivative containing a propargyl group and a sulfonic acid. The propargyl group can be reacted with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield a stable triazole linkage. PEG Linkers can be useful in the development of antibody drug conjugates.
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DC34825 Propargyl-PEG4-methylamine
Propargyl-PEG4-methylamine is a PEG derivative containing a propargyl group and methylamine group. The propargyl group can be reacted with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield a stable triazole linkage. The methylamine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. PEG Linkers are useful in the development of antibody drug conjugates.
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DC34790 Propargyl-PEG7-t-butyl ester
Propargyl-PEG7-t-butyl ester is a PEG derivative containing a propargyl group and a t-butyl protected carboxyl group. The propargyl group can be reacted with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield a stable triazole linkage. The t-butyl protected carboxyl group can be deprotected under acidic conditions. The hydrophilic PEG spacer increases solubility in aqueous media.
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DC34786 Propargyl-PEG2-t-butyl ester
Propargyl-PEG2-t-butyl ester is a PEG derivative containing a propargyl group and a t-butyl protected carboxyl group. The propargyl group can be reacted with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield a stable triazole linkage. The t-butyl protected carboxyl group can be deprotected under acidic conditions. The hydrophilic PEG spacer increases solubility in aqueous media.
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DC34638 Carboxycinnamic acid bishydroxamide
CBHA is a histone deacetylase (HDAC) inhibitor which potently induces transformed cell growth arrest and terminal differentiation.
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DC34618 Galloflavin Potassium
Galloflavin Potassium is an inhibitor of lactate dehydrogenase.
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DC34588 AGN-192403 hydrochloride
AGN-192403 hydrochloride is an I1 imidazoline binding site selective ligand with a potency at I1 comparable to moxonidine, but devoid of affinity for adrenoceptors and the I2 binding site.
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DC34535 CPA
Cyclopiazonic Acid is a natural mycotoxin which inhibits the sarcoplasmic reticulum Ca2+ pump.
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DC34515 SB747651A dihydrochloride
SB-747651A dihydrochloride is a potent MSK1 inhibitor; also inhibiting other AGC group kinases.
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DC34478 ABC44
ABC44 is a potent and selective inhibitor of palmitoyl-protein thioesterase 1 (PPT-1).
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DC34465 ACT-678689
ACT-678689 is a potent inhibitor of tryptophan hydroxylase 1 (TPH1).
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DC34359 Zearalenone
Zearalenone is a mycotoxin produced by Fusarium. It acts by binding the estrogen receptor (ER).
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DC34192 Bisindolylmaleimide I HCl
Bisindolylmaleimide I HCl, also known as GF-109203X HCl, is a specific ATP-competitive PKC inhibitor.
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