Sodium aluminosilicate refers to compounds which contain sodium, aluminium, silicon and oxygen, and which may also contain water. These include synthetic amorphous sodium aluminosilicate, a few naturally occurring minerals and synthetic zeolites. Synthetic amorphous sodium aluminosilicate is widely used as a food additive, E-554.

Decabromobiphenyl is a flame retardant and a standard for environmental testing and research.

21-Desacetyl Deflazacort is a metabolite of Deflazacort (sc-204709), which is a systemic corticosteroid and a derivative of prednisolone. It is used for lupus and rheumatoid arthritis.

Dichloroxylenol is a biochemical. May can be use for endometritis and/or cervicitis.

Coenzyme B12 (adenosylcobalamin; AdoCbl) is a biologically active form of vitamin B12 (Item No. 18425). It belongs to the corrinoid group of compounds, which contain a corrin macrocycle, and is produced only by certain bacteria and archaea. It is a cofactor for various enzymes including mutases, eliminases, aminomutases, and a reductase.2 These enzymes catalyze reactions that generate free radicals through release of the adenosyl group, allowing usually unreactive molecules to become reactive. Only one of these enzymes, methylmalonyl CoA mutase, is found in mammals, therefore, the other enzymes must be taken in through the diet. Genetic mutations in enzymes that synthesize AdoCbl lead to AdoCbl deficiency and methylmalonic aciduria.3 Formulations containing AdoCbl are used to treat patients with this disorder.

Butyl benzoate as involatile solvent, for sampling of isocyanates with silica gel solid phase extraction. Butyl benzoate has been used as preservative in commercial cosmetic lotions. 3-(tert-Butyl)-4-hydroxyphenyl 2,4-dichlorobenzoate (1) was discovered as a moderate FXR antagonist. To improve the potency and the stability of the hit 1, forty derivatives were synthesized and SAR was systematically explored. The results turn out that replacing the 2,4-dichlorophenyl with 2,6-dichloro-4-amidophenyl shows great improvement in potency, replacing the benzoate with benzamide shows improvement in stability and slight declining of potency and 3-(tert-butyl)-4-hydroxyphenyl unit is essential in obtaining the FXR antagonistic activity.

3-Cysteinylacetaminophen TFA salt is an acetaminophen-protein adduct formed during the metabolism of acetaminophen. In mice, 3-cysteinylacetaminophen decreases renal glutathione (GSH) levels --- an effect that can be blocked by the γ-glutamyl inhibitor acivicin.

Febuxostat acyl glucuronide is a metabolite of the xanthine oxidoreductase inhibitor febuxostat. Febuxostat acyl glucuronide is formed via glucuronidation of febuxostat by uridine diphosphate-glucuronosyltransferases (UGTs).

Iloperidone metabolite P88 is an active metabolite of the atypical antipsychotic iloperidone. It binds to the serotonin (5-HT) receptor subtypes 5-HT1B, 5-HT2A, and 5-HT2C, α2b- and α2c-adrenergic, and dopamine D1, D2A, and D4 receptors.

Pyridoxatin is a fungal metabolite that inhibits production of thiobarbituric acid reactive substance (TBARS). Pyridoxatin inhibits hemolysis induced by the free radical generator AAPH and is active against C. albicans.

4-Thiouridine, also known as 4-SU, is a photoactivatable ribonucleoside analog that is widely used for RNA analysis, including short-range RNA-RNA crosslinking and nascent RNA labeling. The crosslinking thio moiety is attached directly to the nucleotide base, thus 4-SU differs from uridine only by a single sulfur substitution. This offers the advantage of incorporating into an RNA chain with minimal structural perturbation and with similar base-pairing properties, reducing the likelihood that substitution will impair RNA interactions or activities.

LP-922056 is a Notum pectinacetylesterase inhibitor which activates wnt signalling. LP-922056 increases cortical bone thickness in a mouse model of bone growth.

D-Kynurenine is an antagonist of hydroxycarboxylic acid receptor 3 HCA3/GPR109B and a metabolite of D-tryptophan. It increases levels of intracellular calcium and decreases forskolin-stimulated production of cAMP in CHO cells expressing human HCA3/GPR109B. D-Kynurenine increases expression of vimentin and decreases expression of E-cadherin in 95D lung cancer cells. It has been used as a substrate in fluorometric assays for D-amino acid oxidase activity.

N-Methyl amisulpride is an impurity of Amisulpride.

Mafenide acetate is a sulfonamide that inhibits the enzyme carbonic anhydrase and is used as topical anti-infective, especially in burn therapy.

Mecobalamin is a biologically active analog of Vitamin B12.

Oxyquinoline sulfate is an antiseptic with mild fungistatic, bacteriostatic, anthelmintic, and amebicidal action. It is also used as a reagent and metal chelator, as a carrier for radio-indium for diagnostic purposes, and its halogenated derivatives are used in addition as topical anti-infective agents and oral antiamebics.

Cupferron is a superoxide dismutase inhibitor.

Ponasterone A is an analog of 20-hydroxy ecdysone. Ecdysteroids act as inducers of ecdysone-inducible mammalian expression systems.

Axitinib sulfoxide is a major metabolite of Axitinib --- a VEGFR tyrosine kinase inhibitor. Axitinib may be useful in cancer therapy.

Rasagiline is a selective and irreversible propargylamine inhibitor of monoamine oxidase type-B (MAO-B) that is not metabolized to amphetamine derivatives. Rasagiline exhibits neuroprotective and antiapoptotic activity against ischemia and several neurotoxins, including SIN-1, MPTP, 6-hydroxydopamine, and N-methyl-(R)-salsolinol.

SPDP-PEG4-NHS ester is a PEG Linker.

SPDP-PEG8-acid is a PEG Linker.

S-acetyl-PEG8-alcohol is a PEG Linker.

S-acetyl-PEG6-alcohol is a PEG Linker.

Lipoamido-PEG3-alcohol is a PEG Linker.

Thiol-PEG3-acid is a PEG derivative containing a thiol group and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The thiol group reacts with maleimide, OPSS, vinylsulfone and transition metal surfaces including gold, silver, etc. The terminal carboxylic acid can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond.

Thiol-PEG2-acid is a PEG derivative containing a thiol group and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The thiol group reacts with maleimide, OPSS, vinylsulfone and transition metal surfaces including gold, silver, etc. The terminal carboxylic acid can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond.

Methyltetrazine-acid is a non-activated amine-reactive building block. In the presence of activators (e.g. EDC, or HATU), it can be used to deriviate amine-containing molecule via a stable amide bond. The low mass weight will add minimal spacer to modified molecules.

Tetrazine-Acid was found to have the fastest kinetics for bioorthogonal reactions where trans-cyclooctene (TCO) was the dienophile. The chemical stability of tetrazines is lower compared to methyltetrazines, but it is in acceptable range and thus can be applied for many applications.