MDK08445 is an important intermediate or precursor for the synthesis of Cefiderocol. MDK08445 has CAS#1225208-44-5. We assigned a code name as MDK08445 (last 5 digital of its CAS# was used). Cefiderocol, also known as S-649266, is a potent siderophore cephalosporin antibiotic with a catechol moiety on the 3-position side chain. S-649266 shows potent in vitro activity against the non-fermenting Gram-negative bacteria Acinetobacter baumannii, Pseudomonas aeruginosa and Stenotrophomonas maltophilia, including MDR strains such as carbapenem-resistant A. baumannii and metallo-β-lactamase-producing P. aeruginosa.

Loratadine specified impurity F is a fluorinated analog of Loratadine, which is a nonsedating-type histamine H1-receptor.

Quinoxyfen is a fungicide of the phenoxyquinoline class used to control powdery mildew, Uncinula necator (Schw.) Burr.

L-Linalool is the key volatile compound of jasmine tea, spruce essential oil and young leaves of Litchi chinensis Sonn.

ICI 216140 is a GRP/bombesin receptor 2 antagonist (IC50 = 2 nM in vitro). At 2 mg/kg, it can reduce bombesin-stimulated pancreatic amylase secretion in rats. At 1 mM, it has been shown to attenuate bombesin-stimulated increases in blood pressure in rats. Bombesin is a peptide, originally isolated from the skin of the European fire-bellied toad, with pressor and sympathoexcitatory activity. Its three receptors are distributed throughout the central and peripheral nervous system and are involved in gastric acid secretion, emotional response, temperature control, learning, and memory. Neuromedin B and gastrin-releasing peptide (GRP) are mammalian homologs of bombesin.

Alanine glutamate is a dipeptide.

L 669262 is a potent HMG-CoA reductase inhibitor.

Ethionine is an antimetabolite and methionine antagonist that interferes with amino acid incorporation into proteins and with cellular ATP utilization. It also produces liver neoplasms.

Ethoprop is a pesticide.

Sodium acetrizoate (rINN, trade names Urokon, Triurol and Salpix), the sodium salt of acetrizoic acid, is a high-osmolality, water-soluble, iodine-based radiographic contrast medium.

alpha-Amyl cinnamaldehyde is a common additive in perfume and cosmetic industry as aroma substance. It is found naturally in the essential oil of chamomile.

C.I. Pigment Red 172 is a Former food dye prohibited from use in foods.

FD&C Yellow No. 5 Aluminum Lake is a synthetic lemon yellow azo dye primarily used as a food coloring.

Phenethyl propionate is the ester of phenethyl alcohol and propionic acid. It can be found in peanuts.

Dexpropranolol hydrochloride is an Anti-Adrenergic (beta-Receptor).

Phosphamidon is an organophosphate cholinesterase inhibitor that is used as an insecticide.

Althiomycin, also known as matamycin, is a thiazole antibiotic, effective against Gram-positive and Gram-negative bacteria. Isolated from Streptomyces matensis, Althiomycin was first described by Margalith et al. in 1959. It acts a protein synthesis inhibitor and its site of action is the 50S subunit of the bacterial ribosome.

Senecionine is an Antineoplastic Agent.

Leucomalachite green is used in detecting latent bloodstains and in the forensic field because of convenience and cost/time-effectiveness.

Picrotoxin, also known as cocculin, is a poisonous crystalline plant compound. Due to its interactions with the inhibitory neurotransmitter GABA, picrotoxin acts as a stimulant and convulsant.

Hydrazobenzene is a biochemical.

4-Aminophenol (or para-aminophenol or p-aminophenol) is the organic compound with the formula H2NC6H4OH. Typically available as a white powder,[2] it was commonly used as a developer for black-and-white film, marketed under the name Rodinal.

4-Isopropoxybenzoic acid is a Selective Inhibitor of Centromere-Associated Protein E.

2-Methylbenzophenone is used in a microfluidic photoreactor.

p-Acetylphenyl acetate is a biochemical.

Diallyl phthalate inhibits algae growth.

Cinnamyl cinnamate is a fragrance chemical.

m-Nitroacetophenone is used for increasing ESI multiple charging of proteins and protein complexes.

Phenylacetaldehyde is an organic compound used in the synthesis of fragrances and polymers.

Monobutyl phthalate affects the expressions of EMT-related proteins and enhances the migration and invasion of MLTC-1 cells.