Novel inhibitor of YycG histidine kinase (HK), showing potent antibiofim activity against Staphylococcus epidermidis

Novel apigenin analogue, suppressing pancreatic stellate cell proliferation

Novel potent orally bioavailable inhibitor of signal transducer and activator of transcription 3 (STAT3)

Novel orally bioavailable STAT3 inhibitor

AMPA Receptor Positive Allosteric Modulator

Novel highly potent HIV-1 inhibitor with broad-spectrum activity (EC50 = 2.0-57 nM) against resistant strains, exhibiting good solubility and safety profiles and a good PK profile with an oral bioavailability of 59% in rats

Novel photoaffinity-labeled probe for full-length human immunodeficiency virus-1 integrase (HIV-1 IN)

Novel enhancer of catalytic efficiency of neurolysin

Novel enhancer of catalytic efficiency of neurolysin

Allosteric inhibitor of ATP phosphoribosyltransferase (ATPPRT), binding to the ATPPRT:ATP complex via a two-step binding mechanism, inhibiting ATPPRT competitively and likely uncompetitively, respectively, against PRPP and ATP

Natural alkaloid, demonstrating significant cytotoxicity against a panel of human and murine tumor cell lines

Novel Potent Inhibitor of HIPK1/HIPK2 Kinase

Natural muscarinic receptor antagonist

Novel HIF Pathway Inhibitor

Novel hypoxia inducible factor hydroxylase modulator

Novel hypoxia inducible factor hydroxylase modulator

Novel HIF-1alpha-p300 Protein Protein Interaction inhibitor

Novel HIF-1alpha inhibitor

CNS active anticonvulsant and ultra-short acting hypnotic

Pentapeptide sequences of hIAPP, being sufficient for the formation of beta-sheet-containing amyloid fibrils and self-assemble laterally into unusually broad ribbons

Hexapeptide sequences of hIAPP, being sufficient for the formation of beta-sheet-containing amyloid fibrils and coiling around each other in a typical amyloid fibril morphology

Potent inhibitor of multidrug-resistant human immunodeficiency virus-1 (HIV-1)

Potent non-nucleoside inhibitor of drug-resistant human immunodeficiency virus (HIV)

Non-nucleoside reverse transcriptase inhibitor

Positive allosteric modulator at the barbiturate/picrotoxin site of the GABAA receptor

Novel sulfur-triazole exchange (SuTEx) covalent probe with ~5-fold enhanced chemoselectivity for tyrosines over other nucleophilic amino acids

Fragment 177-191 of human growth hormone, regulating fat metabolism but without the adverse effects on blood sugar or growth, stimulating lipolysis (the breakdown or destruction of fat) and inhibiting lipogenesis (the transformation of nonfat food materia

Novel type II inhibitor of wild-type and gatekeeper mutants of BCR-ABL, PDGFRalpha, Kit, and Src kinases

Insulin-regulated aminopeptidase (IRAP) inhibitor, mprovin memory in control and memory-deficient mice models

Potent inducer of oxidative stress as well as cell cycle arrest in the S-phase, significantly decreasing intracellular ATP level