Histamine H1 receptor antagonist

Natural inhibitor of dietary fat absorption and showing strong anti-obesity activity

Antibiotic

Novel specific Aurora B inhibitor

Fluorescent indicator of apoptosis, binding the minor groove of DNA at A and T rich regions

Highly potent and selective ligand for the GHB binding sites, binding with 27 times better affinity than GHB itself and acrossing the blood brain barrier in vitro and in vivo

Novel strobilurin acaricide, exhibiting larvicidal and ovicidal activities against various acarids

Novel selective inhibitor of the lymphocytic leukemia (LL) cell survival , Selectively Enhancing the Killing Effect through STAT3 Binding on Lymphocytic Leukemia Cells In Vitro and In Vivo

Novel Blinking Fluorescent Probe for Tubulin Nanoscopy in Living and Fixed Cells

Novel chemical probe for heterochromatin formation and function, disrupting of heterochromatin-mediated transcriptional gene silencing

Novel chemical probe for heterochromatin formation and function, disrupting of heterochromatin-mediated transcriptional gene silencing

Novel Hexosaminidase-Targeting Fluorescence Probe for Visualizing Human Colorectal Cancer.

Novel sialidase-activatable fluorescence probe with improved stability for the sensitive detection of sialidase

Potent and selective I ks channel blocker

Novel food intake-reducing agent

Potent and specific integrin α4ß1 or very late antigen 4 (VLA-4) receptor antagonist, binding to vascular cell adhesion molecule-1 (VCAM-1) and fibronectin

Potent inhibitor of nicotinamide phosphoribosyltransferase (Nampt)

Irriversible inhibitor of GSK3

Protein kinase C partial agonist, targeting the C1 domain, inhibiting cell proliferation, decreasing cell viability and inducing an apoptotic response

Potent stimulator of gamma delta T cells

Novel highly potent, selective, and competitive hMAO-B inhibitor with high BBB permeability profile and neuroprotective action (IC 50 = 42 nM; SI > 2375)

Novel antagonist to the inhibitors of apoptosis (IAPs), potentiating cell death in EGFR-overexpressing non-small-cell lung cancer cells

Potent and highly selective FABP4 inhibitor

Novel Nerve Agent Reactivator

First-in-class inhibitor of protein arginine methyltransferase 5 (PRMT5)

Novel phosphoramidate prodrug of ddhCTP, effectively reducing titers of Zika and West Nile viruses in cell culture with minimal nonspecific toxicity to host cells

Selective Acetylcholinesterase Inhibitor

Novel SARS-CoV-2 Main Protease (Mpro) inhibitor, binding to Subsites S1 and S2 (K d =0.69 µM)

Novel Metformin Derivative; Inhibitor of Proliferation and Invasion of Triple-Negative Breast Cancer Cells

Novel allosteric hexokinase 2 (HK2) modulator, selectively detaching HK2 from the mitochondria