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Cat. No. Product Name Field of Application Chemical Structure
DC20586 XMU-MP-2
XMU-MP-2 is a potent and selective BRK/PTK6 (breast tumor kinase) inhibitor with biochemical IC50 of 3.2 nM.
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DC3129 xl647
XL647 is a novel spectrum-selective kinase inhibitor for EGFR, ErbB2, KDR, Flt-4 and EphB4 with IC50 of 0.3 nM, 16 nM, 1.5 nM, 8.7 nM and 1.4 nM, respectively.
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DC22466 XL-281
XL-281 (BMS 908662) is a potent, selective, orally active inhibitor of wild-type and mutant RAF kinases with anti-tumor activity in multiple xenograft models.
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DC11876 XL 188
XL188 (XL-188) is a potent, selective, non-covalent active-site inhibitor of USP7 with IC50 of 90 nM and 193 nM for USP7 full length enzyme and catalytic domain, respectively.
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DC11248 XL-001
XL-001 (XL001) is a novel specific CB2 inverse agonist with Ki of 0.5 nM.
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DC21006 XF-73
XF-73 (Exeporfinium chloride) is a novel broad-spectrum antibacterial agent that inhibits a range of gram-positive bacterial species (MIC=0.25-4 mg/mL), including Staphylococcus aureus.
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DC21028 XEN-402
XEN-402 (Funapide.
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DC20079 Xanthyletin
Xanthyletin is a coumarin isolated from Citrus, with anti-tumor and anti-bacterial activities. Xanthyletin also inhibits symbiotic fungus cultivated by leaf-cutting ants.
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DC9498 Xanomeline (oxalate)
Xanomeline(LY246708) is a selective M1 muscarinic receptor agonist.
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DC23479 Xamoterol hemifumarate
Xamoterol (ICI 118587) is a third-generation adrenergic β1 adrenergic receptor partial agonist that acts as a cardiac stimulant..
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DC23480 Xamoterol
Xamoterol (ICI 118587) is a third-generation adrenergic β1 adrenergic receptor partial agonist that acts as a cardiac stimulant..
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DC20585 WZ-4-49-8
WZ-4-49-8 is a potent, selective c-Fes protein-tyrosine kinase inhibitor with IC50 of 67 nM.
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DC20584 WYE-151650
WYE-151650 is a novel potent, selective JAK3 inhibitor with IC50 of 0.8 nM, displays 36-, 14-, and 34-fold selectivity against JAK-1, JAK-2, and Tyk-2, respectively.
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DC5088 WYE125132
WYE125132 is a highly potent, ATP-competitive, and specific mTOR kinase inhibitor
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DC23716 WYC-209
WYC-209 is a novel synthetic retinoid that inhibits proliferation of malignant murine melanoma tumor-repopulating cells (TRCs) with IC50 of 0.19 uM, targets retinoic acid receptor (RAR).
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DC10916 WY-135
WY-135 (WY135) is a novel potent inhibitor of ALK and ROS1 with IC50 of 1.2 and 0.48 nM, respectively.
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DC21824 WX-554
WX-554 is an oral, small molecule allosteric inhibitor targeting mitogen-activated protein kinase kinase (MEK1 and MEK2) with an estimated IC50 of 4.7 and 10.7 nM, respectively.
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DC21772 WX-037
WX-037 (UCB-1370037) is a novel small molecule pan class I PI3K inhibitor with IC50 of 4.1, 2.4, 37 and 78 nM for PI3Kα, PI3Kδ, PI3Kγ and PI3Kβ, respectively.
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DC21822 WWL113
WWL113 is a potent inhibitor of Carboxylesterase Ces3 and Ces1f by competitive ABPP of enzymes recombinantly expressed in HEK293T cells (IC50 value of 0.1 uM for each enzyme).
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DC10172 WT-161
WT-161 is a potent and selective HDAC6 inhibitor with an IC50 of 0.40 nM.
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DC7661 WST-3
WST-3 is a highly sensitive tetrazolium reagent (light red) which produces a water-soluble formazan (dark red color).
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DC22265 WS-383 hydrochloride
WS-383 hydrochloride (WS383) is a highly potent, selective, and cellular active inhibitor of DCN1-UBC12 interaction with IC50 of 11 nM.
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DC22264 WS-383
WS-383 (WS383) is a highly potent, selective, and cellular active inhibitor of DCN1-UBC12 interaction with IC50 of 11 nM.
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DC22073 WRG-28
WRG-28 (DDR2 inhibitor WRG-28) is a potent, selective, allosteric inhibitor of discoidin domain receptor 2 (DDR2) with binding IC50 of 230 nM.
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DC22781 WOBE-437
WOBE-437 (WOBE437) is a potent, selective endocannabinoid uptake inhibitor with IC50 of 10 nM, with an outstanding 1,000-fold selectivity over FAAH.
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DC11132 Wnt-p53 inhibitor compound 2
Wnt-p53 inhibitor compound 2 is a novel inhibitor targets both Wnt signaling and ATM/p53, potently inhibits Wnt transcription (IC50=11 nM) and p53 transcription (EC50=1.9 nM).
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DC23889 Wntepane 1
Wntepane 1 is a small-molecule activator of the Wnt pathway that modulates the van-Gogh-like receptor 1 (Vangl1), activates Wnt signaling with EC50 of 1.8 uM in the reporter gene assay.
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DC7433 IWP-2-V2
Wnt signaling proteins are small secreted proteins that are active in embryonic development, tissue homeostasis, and tumorigenesis.1,2,3Wnt proteins bind to receptors on the cell surface, initiating a signaling cascade that leads to β-catenin activation of gene transcription. IWP-2 (Item No. 13951) is an inhibitor of Wnt production (IC50 = 27 nM) that inactivates porcupine, a membrane-bound O-acyltransferase whose palmitoylation activity is essential For the signaling ability and secretion of Wnt proteins.4 IWP-2-V2 is a less potent IWP-2 derivative whose chemical structure retains the benzothiazole group of its parent compound.4 It has been used to determine which structural features of IWP-2 are essential For impairing Wnt/β-catenin pathway activity.4For the detailed information of IWP-2-V2, the solubility of IWP-2-V2 in water, the solubility of IWP-2-V2 in DMSO, the solubility of IWP-2-V2 in PBS buffer, the animal experiment (test) of IWP-2-V2, the cell expriment (test) of IWP-2-V2, the in vivo, in vitro and clinical trial test of IWP-2-V2, the EC50, IC50,and Affinity of IWP-2-V2, Please contact DC Chemicals..
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DC20582 Withaferin A
Withaferin A is a steroid lactone that displays anti-inflammatory, antitumor and antiangiogenic activity, potently inhibits NF-κB activation by preventing the TNF-induced activation of IKKβ via a thioalkylation-sensitive redox mechanism.
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DC23306 WF-210
WF-210 is a PAC-1 derivative and potent activator of procaspases-3 with EC50 of 0.95 uM, displays more cytotoxic than PAC‐1 to human cancer cells, but less cytotoxic to normal cells.
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