MFN2 agonist B-A/l is a mall-molecule mimics of the peptide-peptide interface of MFN2, allosterically activates MFN2 and promotes mitochondrial fusion with EC50 of 3 nM.

MFA-1 (Merck FXR agonist 1) is a potent, synthetic FXR agonist with EC50 of 16.9 nM in coactivator recruitment assays, displays 500-fold more potent than CDCA.

MF498 is a novel and selective E prostanoid receptor 4 (EP4) inhibitor, relieves joint inflammation and pain in rodent models of rheumatoid and osteoarthritis.

MF266-1 is a potent, selective prostaglandin E receptor subtype 1 (EP1) antagonist with Ki of 3.8 nM, displayes a relatively good selectivity over other prostanoid receptors..

Mevastatin (Compactin; ML236B) inhibits HMGCR (HMG-CoA reductase) (Ki for acid form is 1 nM) which in turn inhibits isoprenoid biosynthesis and therefore blocks protein isoprenylation and reduces plasma cholesterol levels in humans.

Metronidazole Benzoate is the benzoate ester of metronidazole, a synthetic nitroimidazole derivative with antiprotozoal and antibacterial activities.

Metoprolol is a cardioselective β1-adrenergic blocking agent.

Metolazone (Zaroxolyn)

Metixene hydrochloride hydrate is an anticholinergic antiparkinsonian agent, potently inhibits binding of quinuclidinyl benzilate (QNB) to the muscarinic receptor in rat brain cortical tissue, with an IC50 of 55 nM and a Kd of 15 nM.

Methylproamine is a DNA-binding radioprotector which, on the basis of published pulse radiolysis studies, acts by repair of transient radiation-induced oxidative species on DNA.

Methylprednisolone

Methyliodobikinin is a potent bikinin-like inhibitor targeting GSK3/Shaggy-like kinase, shows improved cell permeability, highly potent in vivo although it had lower activity in vitro.

Methyl Gerfelin (M-GFN) is an osteoclastogenesis inhibitor (IC50=2.8 uM) through the competitive inhibition of glyoxalase I (GLO1) with Ki of 0.23 uM.

Methyl 13-cis-4-Oxoretinoate is a bioactive chemical.

Methoxy-PEPy is a potent, selective mGlu5 receptor antagonist with IC50 of 1 nM.

Methoxsalen (Oxsoralen)

Methotrexate(WR19039; CL14377) can interfere with the growth of certain cells of the body, especially cells that reproduce quickly, such as cancer cells, bone marrow cells, and skin cells.

Methocarbamol is a central muscle relaxant used to treat skeletal muscle spasms.

Methimazole(Tapazole, Northyx) is an antithyroid medicine.

MethADP is a specific CD73 inhibitor.

Methacycline HCl (Physiomycine)

Metformin HCl(Glucophage)

Metesind glucuronate (AG 331.

Metaxalone(AHR438;NSC170959) is a muscle relaxant used to relax muscles.

Metadoxine blocks adipocyte differentiation in association with inhibition of the protein kinase A-cAMP response element binding protein (PKA-CREB) pathway.

Mestranol

Meropenem

Mequitazine is a potent, nonsedative and long-acting histamine H1 antagonist.

Meloxicam (Mobic)

MELK inhibitor 17 is a potent, selective MELK inhibitor with Ki/IC50 of 0.39/3 nM, >100-fold selectivity over CHK1, CAMKK2, NUAK1 and ERK2.