BKT-300 is a potent and selective inhibitor of Protein regulator of cytokinesis 1 (PRC1) with a Kd of 28.3 nM. It disrupts microtubule organization, inducing G2/M arrest, mitotic catastrophe, and caspase-3–dependent apoptosis, and shows promise as a research treatment for advanced acute myeloid leukemia (AML).

ATP dimagnesium (Adenosine 5'-triphosphate dimagnesium) is a central molecule in energy metabolism, driving cellular pumps and acting as a coenzyme. It also functions as an endogenous signaling molecule that modulates immune responses and activates the NLRP3 inflammasome, contributing to host defense during bacterial infections.

ABD0171 is a potent, irreversible, and selective inhibitor of aldehyde dehydrogenase 1A3 (ALDH1A3), with an IC50 of 0.34 µM using the physiological substrate all-trans-retinaldehyde (atRAL). It also inhibits ALDH1A2 and ALDH1A1 with IC50 of 0.79 µM and 6.6 µM, respectively. ABD0171 disrupts key oncogenic pathways in triple-negative breast cancer (TNBC) cells in vitro and exhibits robust antitumor and antimetastatic activity in vivo.

6K465 is a pyrimidine-based inhibitor of Aurora A, that reduces levels of c-MYC and N-MYC oncoproteins. It demonstrates compelling antitumor efficacy.

2-bromoethanol-d4 is the deuterated derivative of 2-bromoethanol. 2-bromoethanol is a cytotoxic alkylating agent.

1-Methyl-1,4-piperazine-d8 is the deuterated derivative of 1-methyl-piperazine.

(S)-Terazosin is a potent and selective antagonist of α-adrenoceptor with Ki values of 3.91 nM, 0.79 nM and 1.16 nM for α1a, α1b and α1d-adrenoceptor, respectively. It also has high-affinity for α2a, α2B and α2c-adrenoceptor with Ki values of 729 nM, 3.5 nM and 46.4 nM, respectively. It may prove to be a useful probe in understanding the functional role of subtypes of adrenoceptors in various tissues.

(D5)epichlorohydrin is the deuterated form of epichlorohydrin. Epichlorohydrin is a highly toxic industrial raw material with alkylating activity.

Trimecaine, a local neural blockade agent, has a strong depressant effect on the cerebral cortex and the ascending reticular formation of the brain stem.

Triglyceride OLO,sn (Compound 2) is a triglycerides that can be isolated from Dirca palustris.

SU-740 is a chalcone derivative with anti-ulcer activity.

Sporidesmolide III is a cyclodepsipeptide originally isolated from P. chartarum.

PSSI-51 is an orally active, peripherally selective inhibitor of succinyl-CoA:3-ketoacid-CoA transferase (SCOT). PSSI-51 inhibits SCOT activity in peripheral tissues (such as muscle and kidney) but does not affect SCOT activity in brain tissue. PSSI-51 reduces ketone body oxidation by inhibiting SCOT, thereby improving obesity-related hyperglycemia. PSSI-51 can be used in the study of type 2 diabetes (T2D) and has the potential to improve obesity-related metabolic disorders.

Phenylacetyl Coenzyme A (Phenylacetyl Coenzyme A) tetrasodium is an effector molecule of the TetR family transcriptional repressor PaaR. Phenylacetyl Coenzyme A tetrasodium changes the conformation of PaaR, causing it to dissociate from DNA and initiate transcription. Phenylacetyl Coenzyme A tetrasodium is promising for research of microbial metabolism.

Pentolinium tartrate is a ganglionic blocking agent. Pentolinium tartrate lowers blood pressure and permits regression of the signs and symptoms associated with severe hypertension.

L-Serine-S2-PEG-Formic acid is a linker for FGT-4.

Leptosin I is found in the strain of Leptosphaeria sp. OUPS-4. Leptosin I inhibits Leukemia lymphocyte P388 in culture with an ED50 of 1.13 μg/mL.

Laudexium methylsulfate is a neuromuscular blocking agent or skeletal muscle relaxant and a nondepolarizing neuromuscular blocking agent.

Larubrilstat is a vascular non-inflammatory molecule-1 (VNN1) inhibitor.

Laporolimus is an immunosuppressant.

Kibdelone C is a flavonoid compound found in Kibdelosporangium sp. with anticancer activity, exhibiting GI50 values of less than 1 nM against leukemia cell lines (SR) and renal cancer cell lines (SN12C). Kibdelone C is promising for anticancer research.

KB-208 is a phagocytosis inhibitor that improves immune thrombocytopenia (ITP) in mouse models at a dose of 1 mg/kg. KB-208 does not affect other blood parameters and does not elevate serum toxicity biomarkers. KB-208 can be used in immunology research.

Fenoxazoline is a decongestant and a vasoconstrictor.

FA-15 is an phenolic antioxidant. FA-15 has effect on stabilization of reactive fuels.

Ethyl 4-(butylamino)benzoate is an N-alkylated ester derivative of aminobenzoic acid.

DL-Theanine (DL-Glutamic acid γ-ethyl amide) is a natural compound showing tranquilizing effects in the brain.

Cumyl-chsinaca is a synthetic cannabinoid containing indazole-3-carboxamide

BPH-742 (compound 9) is a Geranylgeranyl diphosphate synthase inhibitor with IC50 of 0.1 μM. BPH-742 has antitumor activity.

BPH-628 is an aromatic geranylgeranyl diphosphate synthase (GGPPS) inhibitor, with a pIC50 of 6.1.

BCX-3607 is an orally active tissue factor/factor VIIa (TF-FVIIa) inhibitor (IC50: 4 nM). BCX-3607 blocks the extrinsic coagulation pathway by inhibiting the TF-FVIIa complex and significantly prolongs the prothrombin time (PT). BCX-3607 has a higher selectivity for TF-FVIIa than other serine proteases (such as thrombin, FXa, etc.). BCX-3607 can reduce thrombus weight and inflammatory response, and has both anti-thrombotic and anti-inflammatory effects. BCX-3607 can be used in the study of thrombosis-related diseases.