CPI-268456|cas 1380087-86-4|DC Chemicals

Cas No.:	1380087-86-4
Chemical Name:	CPI-268456
Synonyms:	CPI-268456
SMILES:	NC(=O)C[C@@H]1C2=C(C(C)=NO2)C3C(=CC(Cl)=CC=3)C(C4=CC=C(Cl)C=C4)=N1
Formula:	C₂₀H₁₅N₃O₂Cl₂
M.Wt:	400.258
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Cat. No.	Product name	Field of application
DC9724	BI-7273	BI-7273 is a potent, selective, and cell-permeable BRD9 BD Inhibitor.
DC70466	GSK549	GSK549 (GSK-549) is a potent, highly selective, BD2 domain-selective BET inhibitor with pIC50 of 7.8 (BRD4 BD2), 1150-fold selectivity over BD1.
DC11261	ZL0420	ZL0420 is a potent, highly selective BRD4 inhibitor with IC50 of 27 and 32 nM for BRD4-BD1 and BRD4-BD2, respectively.
DC8261	(-)-JQ-1	The (-)-JQ1 stereoisomer has no appreciable affinity to BET bromodomains，it is the negative control of +JQ-1.
DC8320	RVX-208	RVX-208(RVX 000222) is a small molecule that increases apolipoprotein A-I and high-density lipoprotein cholesterol in vitro and in vivo; is a BET bromodomain antagonist.
DC10786	PLX51107	PLX51107 is a novel BET inhibitor with a unique binding mode in the acetylated lysine binding pocket of BRD4 that differentiates it from other compounds under investigation.
DC8291	PFI-4	PFI-4 is a potent and selective BRPF1 bromodomain inhibitor (IC50 = 80 nM).
DC7649	PFI-3	PFI-3 is a novel potent, selective and cell permeable inhibitor of SMARCA4 and PB1(5) bromodomains with IC50 ~ 89 nM and 48 nM respectively.
DC9305	PF-CBP1(PF-06670910) hydrochloride	PF-CBP1 is potent and highly-selective inhibitor of the bromodomain of CREB binding protein (CBP BRD) that down regulates targets of CBP in macrophages primary neurons.
DC7850	OF-1	OF-1 is a potent inhibitor of BRPF1B and BRPF2 bromodomain with Kd of 100 nM and 500 nM, respectively.