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| Cas No.: | 72956-09-3 |
| Chemical Name: | Carvedilol (free base) |
| SMILES: | OC(COC1C2C3C=CC=CC=3NC=2C=CC=1)CNCCOC1C(OC)=CC=CC=1 |
| Formula: | C24H26N2O4 |
| M.Wt: | 406.47 |
| Purity: | >98% |
| Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: | Carvedilol(BM14190) is a non-selective beta blocker/alpha-1 blocker with an IC50 of 3.8 μM for inhibition of LDL oxidation.Carvedilol is a nonselective-blocking agent and is used in the treatment of hypertension and angina pectoris. As a third-generation β-adrenergic blocker (β-blocker), Carvedilol is able to reverse cardiac structural remodeling. Recentresults demonstrated that the effect caused by Carvedilol on cardiac remodeling is largely dependent on endogenous NO. |