DC42357|CAS 2387524-59-4|DC Chemicals

Cas No.:	2387524-59-4
Chemical Name:	NF-kappaBeta activator 1
Synonyms:	NF-κΒ activator 1;NF-kappaBeta activator 1;3-[2-(2-Fluoroanilino)-1,3-thiazol-4-yl]benzoic acid
SMILES:	S1C([H])=C(C2C([H])=C([H])C([H])=C(C(=O)O[H])C=2[H])N=C1N([H])C1=C([H])C([H])=C([H])C([H])=C1F
Formula:	C₁₆H₁₁FN₂O₂S
M.Wt:	314.3341
Purity:	98%
Sotrage:	Please store the product under the recommended conditions in the Certificate of Analysis.

Cat. No.	Product name	Field of application
DC42357	NF-κΒ activator 1	NF-κΒ activator 1 is a potent NF-κΒ activator with an EC50 of 0.9 μM. NF-κΒ activator 1 induces superoxide dismutase (SOD) 2 mRNA expression.
DC10636	SC75741	SC75741 is a potent NF-κB inhibitor with EC50 of 200 nM.
DC7741	JSH-23	JSH-23 is an inhibitor of NF-κB transcriptional activity with IC50 of 7.1 μM.
DC10768	IT 901	IT 901 is a c-Rel inhibitor (IC50 = 3 μM). Inhibits IL-2 expression in activated T-cells in vitro.
DC8827	Didox	Didox is a simple, synthetic antioxidant that has been found to reduce the levels of oxidative injury markers.
DC8038	Bay 11-7085	BAY 11-7085 is an irreversible inhibitor of TNFα-induced IκBα phosphorylation with an IC50 value of 10 μM.
DC7869	BAY11-7082	BAY 11-7082 is a NF-κB inhibitor, inhibits TNFα-induced IκBα phosphorylation with IC50 of 10 μM. Also inhibiting components of the ubiquitin system.

NF-κΒ activator 1